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Page 1
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.
Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Abou Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, Wallen TJ, Wohlford-Lenane C, McMenimen JD, Chen JH, Bogan KL, Adam RJ, Hornick EE, Nelson GA 4th, Hoffman EA, Chang EH, Zabner J, McCray PB Jr, Prather RS, Meyerholz DK, Welsh MJ. Stoltz DA, et al. Among authors: hoffman ea. J Clin Invest. 2013 Jun;123(6):2685-93. doi: 10.1172/JCI68867. Epub 2013 May 8. J Clin Invest. 2013. PMID: 23676501 Free PMC article.
Air trapping and airflow obstruction in newborn cystic fibrosis piglets.
Adam RJ, Michalski AS, Bauer C, Abou Alaiwa MH, Gross TJ, Awadalla MS, Bouzek DC, Gansemer ND, Taft PJ, Hoegger MJ, Diwakar A, Ochs M, Reinhardt JM, Hoffman EA, Beichel RR, Meyerholz DK, Stoltz DA. Adam RJ, et al. Among authors: hoffman ea. Am J Respir Crit Care Med. 2013 Dec 15;188(12):1434-41. doi: 10.1164/rccm.201307-1268OC. Am J Respir Crit Care Med. 2013. PMID: 24168209 Free PMC article.
Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs.
Hoegger MJ, Awadalla M, Namati E, Itani OA, Fischer AJ, Tucker AJ, Adam RJ, McLennan G, Hoffman EA, Stoltz DA, Welsh MJ. Hoegger MJ, et al. Among authors: hoffman ea. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2355-60. doi: 10.1073/pnas.1323633111. Epub 2014 Jan 28. Proc Natl Acad Sci U S A. 2014. PMID: 24474805 Free PMC article.
Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities.
Adam RJ, Hisert KB, Dodd JD, Grogan B, Launspach JL, Barnes JK, Gallagher CG, Sieren JP, Gross TJ, Fischer AJ, Cavanaugh JE, Hoffman EA, Singh PK, Welsh MJ, McKone EF, Stoltz DA. Adam RJ, et al. Among authors: hoffman ea. JCI Insight. 2016 Apr 7;1(4):e86183. doi: 10.1172/jci.insight.86183. JCI Insight. 2016. PMID: 27158673 Free PMC article.
Postnatal airway growth in cystic fibrosis piglets.
Adam RJ, Abou Alaiwa MH, Bouzek DC, Cook DP, Gansemer ND, Taft PJ, Powers LS, Stroik MR, Hoegger MJ, McMenimen JD, Hoffman EA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA. Adam RJ, et al. Among authors: hoffman ea. J Appl Physiol (1985). 2017 Sep 1;123(3):526-533. doi: 10.1152/japplphysiol.00263.2017. Epub 2017 Jun 15. J Appl Physiol (1985). 2017. PMID: 28620056 Free PMC article.
Mucus strands from submucosal glands initiate mucociliary transport of large particles.
Fischer AJ, Pino-Argumedo MI, Hilkin BM, Shanrock CR, Gansemer ND, Chaly AL, Zarei K, Allen PD, Ostedgaard LS, Hoffman EA, Stoltz DA, Welsh MJ, Alaiwa MHA. Fischer AJ, et al. Among authors: hoffman ea. JCI Insight. 2019 Jan 10;4(1):e124863. doi: 10.1172/jci.insight.124863. JCI Insight. 2019. PMID: 30626743 Free PMC article.
664 results