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Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers.
Nakada EM, Bhakta NR, Korwin-Mihavics BR, Kumar A, Chamberlain N, Bruno SR, Chapman DG, Hoffman SM, Daphtary N, Aliyeva M, Irvin CG, Dixon AE, Woodruff PG, Amin S, Poynter ME, Desai DH, Anathy V. Nakada EM, et al. Among authors: hoffman sm. JCI Insight. 2019 May 2;4(9):e98101. doi: 10.1172/jci.insight.98101. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045581 Free PMC article.
Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness.
Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff PG, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, Poynter ME, Anathy V. Hoffman SM, et al. J Allergy Clin Immunol. 2016 Mar;137(3):822-32.e7. doi: 10.1016/j.jaci.2015.08.018. Epub 2015 Oct 4. J Allergy Clin Immunol. 2016. PMID: 26435004 Free PMC article.
Effect of a chemical chaperone, tauroursodeoxycholic acid, on HDM-induced allergic airway disease.
Siddesha JM, Nakada EM, Mihavics BR, Hoffman SM, Rattu GK, Chamberlain N, Cahoon JM, Lahue KG, Daphtary N, Aliyeva M, Chapman DG, Desai DH, Poynter ME, Anathy V. Siddesha JM, et al. Among authors: hoffman sm. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1243-59. doi: 10.1152/ajplung.00396.2015. Epub 2016 May 6. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27154200 Free PMC article.
The Duffy antigen receptor for chemokines regulates asthma pathophysiology.
Chapman DG, Mougey EB, Van der Velden JL, Lahue KG, Aliyeva M, Daphtary N, George KL, Hoffman SM, Schneider RW, Tracy RP, Worthen GS, Poynter ME, Peters SP, Lima JJ, Janssen-Heininger YMW, Irvin CG. Chapman DG, et al. Among authors: hoffman sm. Clin Exp Allergy. 2017 Sep;47(9):1214-1222. doi: 10.1111/cea.12949. Epub 2017 Jun 9. Clin Exp Allergy. 2017. PMID: 28471517 Free PMC article.
Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease.
Hoffman SM, Tully JE, Lahue KG, Anathy V, Nolin JD, Guala AS, van der Velden JL, Ho YS, Aliyeva M, Daphtary N, Lundblad LK, Irvin CG, Janssen-Heininger YM. Hoffman SM, et al. Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L528-38. doi: 10.1152/ajplung.00167.2012. Epub 2012 Jun 29. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22752969 Free PMC article.
Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation.
van der Velden JL, Hoffman SM, Alcorn JF, Tully JE, Chapman DG, Lahue KG, Guala AS, Lundblad LK, Aliyeva M, Daphtary N, Irvin CG, Janssen-Heininger YM. van der Velden JL, et al. Among authors: hoffman sm. Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L866-75. doi: 10.1152/ajplung.00153.2013. Epub 2014 Mar 7. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24610935 Free PMC article.
Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice.
Hoffman SM, Qian X, Nolin JD, Chapman DG, Chia SB, Lahue KG, Schneider R, Ather JL, Randall MJ, McMillan DH, Jones JT, Taatjes DJ, Aliyeva M, Daphtary N, Abdalla S, Lundblad LK, Ho YS, Anathy V, Irvin CG, Wouters EF, Reynaert NL, Dixon AE, van der Vliet A, Poynter ME, Janssen-Heininger YM. Hoffman SM, et al. Am J Respir Cell Mol Biol. 2016 Sep;55(3):377-86. doi: 10.1165/rcmb.2015-0401OC. Am J Respir Cell Mol Biol. 2016. PMID: 27035878 Free PMC article.
Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics.
Chamberlain N, Korwin-Mihavics BR, Nakada EM, Bruno SR, Heppner DE, Chapman DG, Hoffman SM, van der Vliet A, Suratt BT, Dienz O, Alcorn JF, Anathy V. Chamberlain N, et al. Among authors: hoffman sm. Redox Biol. 2019 Apr;22:101129. doi: 10.1016/j.redox.2019.101129. Epub 2019 Jan 29. Redox Biol. 2019. PMID: 30735910 Free PMC article.
89 results