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Structure-based design of bacterial nitric oxide synthase inhibitors.
Holden JK, Kang S, Hollingsworth SA, Li H, Lim N, Chen S, Huang H, Xue F, Tang W, Silverman RB, Poulos TL. Holden JK, et al. Among authors: hollingsworth sa. J Med Chem. 2015 Jan 22;58(2):994-1004. doi: 10.1021/jm501723p. Epub 2015 Jan 6. J Med Chem. 2015. PMID: 25522110 Free PMC article.
Crystal structure of cindoxin, the P450cin redox partner.
Madrona Y, Hollingsworth SA, Tripathi S, Fields JB, Rwigema JC, Tobias DJ, Poulos TL. Madrona Y, et al. Among authors: hollingsworth sa. Biochemistry. 2014 Mar 11;53(9):1435-46. doi: 10.1021/bi500010m. Epub 2014 Feb 25. Biochemistry. 2014. PMID: 24533927 Free PMC article.
Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic Index.
Pissarnitski DA, Kekec A, Yan L, Zhu Y, Feng DD, Huo P, Madsen-Duggan C, Moyes CR, Nargund RP, Kelly T, Zhang X, Carballo-Jane E, Gorski J, Zafian P, Qatanani M, Kaarsholm N, Meng F, Jia X, Lee KJ, Wang W, Xu S, Hohn MJ, Iammarino MJ, McCoy MA, Okoh GA, Liang Y, Hollingsworth SA, Erion MD, Kelley DE, Garbaccio RM, Zhang A, Mu J, Lin S. Pissarnitski DA, et al. Among authors: hollingsworth sa. J Med Chem. 2022 Apr 14;65(7):5593-5605. doi: 10.1021/acs.jmedchem.1c02073. Epub 2022 Mar 17. J Med Chem. 2022. PMID: 35298158
36 results