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Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice.
Polyzos AA, Lee DY, Datta R, Hauser M, Budworth H, Holt A, Mihalik S, Goldschmidt P, Frankel K, Trego K, Bennett MJ, Vockley J, Xu K, Gratton E, McMurray CT. Polyzos AA, et al. Among authors: holt a. Cell Metab. 2019 Jun 4;29(6):1258-1273.e11. doi: 10.1016/j.cmet.2019.03.004. Epub 2019 Mar 28. Cell Metab. 2019. PMID: 30930170 Free PMC article.
Rapid and pervasive changes in genome-wide enhancer usage during mammalian development.
Nord AS, Blow MJ, Attanasio C, Akiyama JA, Holt A, Hosseini R, Phouanenavong S, Plajzer-Frick I, Shoukry M, Afzal V, Rubenstein JL, Rubin EM, Pennacchio LA, Visel A. Nord AS, et al. Among authors: holt a. Cell. 2013 Dec 19;155(7):1521-31. doi: 10.1016/j.cell.2013.11.033. Cell. 2013. PMID: 24360275 Free PMC article.
A high-resolution enhancer atlas of the developing telencephalon.
Visel A, Taher L, Girgis H, May D, Golonzhka O, Hoch RV, McKinsey GL, Pattabiraman K, Silberberg SN, Blow MJ, Hansen DV, Nord AS, Akiyama JA, Holt A, Hosseini R, Phouanenavong S, Plajzer-Frick I, Shoukry M, Afzal V, Kaplan T, Kriegstein AR, Rubin EM, Ovcharenko I, Pennacchio LA, Rubenstein JL. Visel A, et al. Among authors: holt a. Cell. 2013 Feb 14;152(4):895-908. doi: 10.1016/j.cell.2012.12.041. Epub 2013 Jan 31. Cell. 2013. PMID: 23375746 Free PMC article.
Human-specific gain of function in a developmental enhancer.
Prabhakar S, Visel A, Akiyama JA, Shoukry M, Lewis KD, Holt A, Plajzer-Frick I, Morrison H, Fitzpatrick DR, Afzal V, Pennacchio LA, Rubin EM, Noonan JP. Prabhakar S, et al. Among authors: holt a. Science. 2008 Sep 5;321(5894):1346-50. doi: 10.1126/science.1159974. Science. 2008. PMID: 18772437 Free PMC article.
ChIP-seq accurately predicts tissue-specific activity of enhancers.
Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Ren B, Rubin EM, Pennacchio LA. Visel A, et al. Among authors: holt a. Nature. 2009 Feb 12;457(7231):854-8. doi: 10.1038/nature07730. Nature. 2009. PMID: 19212405 Free PMC article.
In vivo characterization of a vertebrate ultraconserved enhancer.
Poulin F, Nobrega MA, Plajzer-Frick I, Holt A, Afzal V, Rubin EM, Pennacchio LA. Poulin F, et al. Among authors: holt a. Genomics. 2005 Jun;85(6):774-81. doi: 10.1016/j.ygeno.2005.03.003. Epub 2005 Apr 15. Genomics. 2005. PMID: 15885503
590 results