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Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.
Dvorak K, Chavarria M, Payne CM, Ramsey L, Crowley-Weber C, Dvorakova B, Dvorak B, Bernstein H, Holubec H, Sampliner RE, Bernstein C, Prasad A, Green SB, Garewal H. Dvorak K, et al. Among authors: holubec h. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5305-13. doi: 10.1158/1078-0432.CCR-07-0483. Clin Cancer Res. 2007. PMID: 17875759
Crypt-restricted loss and decreased protein expression of cytochrome C oxidase subunit I as potential hypothesis-driven biomarkers of colon cancer risk.
Payne CM, Holubec H, Bernstein C, Bernstein H, Dvorak K, Green SB, Wilson M, Dall'Agnol M, Dvorakova B, Warneke J, Garewal H. Payne CM, et al. Among authors: holubec h. Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2066-75. doi: 10.1158/1055-9965.EPI-05-0180. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 16172211
Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus.
Dvorak K, Payne CM, Chavarria M, Ramsey L, Dvorakova B, Bernstein H, Holubec H, Sampliner RE, Guy N, Condon A, Bernstein C, Green SB, Prasad A, Garewal HS. Dvorak K, et al. Among authors: holubec h. Gut. 2007 Jun;56(6):763-71. doi: 10.1136/gut.2006.103697. Epub 2006 Dec 4. Gut. 2007. PMID: 17145738 Free PMC article.
Deoxycholate, an endogenous tumor promoter and DNA damaging agent, modulates BRCA-1 expression in apoptosis-sensitive epithelial cells: loss of BRCA-1 expression in colonic adenocarcinomas.
Romagnolo DF, Chirnomas RB, Ku J, Jeffy BD, Payne CM, Holubec H, Ramsey L, Bernstein H, Bernstein C, Kunke K, Bhattacharyya A, Warneke J, Garewal H. Romagnolo DF, et al. Among authors: holubec h. Nutr Cancer. 2003;46(1):82-92. doi: 10.1207/S15327914NC4601_11. Nutr Cancer. 2003. PMID: 12925308
A proteomic study of resistance to deoxycholate-induced apoptosis.
Bernstein H, Payne CM, Kunke K, Crowley-Weber CL, Waltmire CN, Dvorakova K, Holubec H, Bernstein C, Vaillancourt RR, Raynes DA, Guerriero V, Garewal H. Bernstein H, et al. Among authors: holubec h. Carcinogenesis. 2004 May;25(5):681-92. doi: 10.1093/carcin/bgh072. Epub 2004 Jan 16. Carcinogenesis. 2004. PMID: 14729586
49 results