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Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction.
Borchert A, Kalms J, Roth SR, Rademacher M, Schmidt A, Holzhutter HG, Kuhn H, Scheerer P. Borchert A, et al. Among authors: holzhutter hg. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1095-1107. doi: 10.1016/j.bbalip.2018.06.006. Epub 2018 Jun 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29883798
The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity.
Kalms J, Banthiya S, Galemou Yoga E, Hamberg M, Holzhutter HG, Kuhn H, Scheerer P. Kalms J, et al. Among authors: holzhutter hg. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):463-473. doi: 10.1016/j.bbalip.2017.01.003. Epub 2017 Jan 14. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28093240
Dual role of oxygen during lipoxygenase reactions.
Ivanov I, Saam J, Kuhn H, Holzhütter HG. Ivanov I, et al. Among authors: holzhutter hg. FEBS J. 2005 May;272(10):2523-35. doi: 10.1111/j.1742-4658.2005.04673.x. FEBS J. 2005. PMID: 15885101 Free article.
The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches.
Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ. Brosig A, et al. Among authors: holzhutter hg. Cell Rep. 2019 Nov 12;29(7):2028-2040.e8. doi: 10.1016/j.celrep.2019.10.039. Cell Rep. 2019. PMID: 31722215 Free PMC article.
180 results