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Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-Based Platform: An In vitro Disease Model of Atrial Arrhythmias.
Nakanishi H, Lee JK, Miwa K, Masuyama K, Yasutake H, Li J, Tomoyama S, Honda Y, Deguchi J, Tsujimoto S, Hidaka K, Miyagawa S, Sawa Y, Komuro I, Sakata Y. Nakanishi H, et al. Among authors: honda y. Front Physiol. 2019 Jun 27;10:818. doi: 10.3389/fphys.2019.00818. eCollection 2019. Front Physiol. 2019. PMID: 31316396 Free PMC article.
CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability.
Nozaki Y, Honda Y, Watanabe H, Saiki S, Koyabu K, Itoh T, Nagasawa C, Nakamori C, Nakayama C, Iwasaki H, Suzuki S, Washio I, Takahashi E, Miyamoto K, Yamanishi A, Endo H, Shinozaki J, Nogawa H, Kunimatsu T. Nozaki Y, et al. Among authors: honda y. Regul Toxicol Pharmacol. 2016 Jun;77:75-86. doi: 10.1016/j.yrtph.2016.02.007. Epub 2016 Feb 13. Regul Toxicol Pharmacol. 2016. PMID: 26884090
CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information.
Nozaki Y, Honda Y, Watanabe H, Saiki S, Koyabu K, Itoh T, Nagasawa C, Nakamori C, Nakayama C, Iwasaki H, Suzuki S, Tanaka K, Takahashi E, Miyamoto K, Morimura K, Yamanishi A, Endo H, Shinozaki J, Nogawa H, Shinozawa T, Saito F, Kunimatsu T. Nozaki Y, et al. Among authors: honda y. Regul Toxicol Pharmacol. 2017 Aug;88:238-251. doi: 10.1016/j.yrtph.2017.06.006. Epub 2017 Jun 17. Regul Toxicol Pharmacol. 2017. PMID: 28634147
2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): a potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivation of CYP3A.
Nishio Y, Kimura H, Sawada N, Sugaru E, Horiguchi M, Ono M, Furuta Y, Sakai M, Masui Y, Otani M, Hashizuka T, Honda Y, Deguchi J, Nakagawa T, Nakahira H. Nishio Y, et al. Among authors: honda y. Bioorg Med Chem. 2011 Sep 15;19(18):5490-9. doi: 10.1016/j.bmc.2011.07.042. Epub 2011 Aug 4. Bioorg Med Chem. 2011. PMID: 21865048
Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes.
Asakura K, Hayashi S, Ojima A, Taniguchi T, Miyamoto N, Nakamori C, Nagasawa C, Kitamura T, Osada T, Honda Y, Kasai C, Ando H, Kanda Y, Sekino Y, Sawada K. Asakura K, et al. Among authors: honda y. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:17-26. doi: 10.1016/j.vascn.2015.04.002. Epub 2015 Apr 22. J Pharmacol Toxicol Methods. 2015. PMID: 25910965 Free article.
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[No authors listed] [No authors listed] PMID: 31962938
3,096 results