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The use of CRISPR to generate a whole-gene humanized MAPT and the examination of P301L and G272V clinical variants, along with the creation of deletion null alleles of ptl-1, pgrn-1 and alfa-1 loci.
Lins J, Hopkins CE, Brock T, Hart AC. Lins J, et al. Among authors: hopkins ce. MicroPubl Biol. 2022 Sep 19;2022:10.17912/micropub.biology.000615. doi: 10.17912/micropub.biology.000615. eCollection 2022. MicroPubl Biol. 2022. PMID: 36204657 Free PMC article.
SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells.
Jackson J, Wischhof L, Scifo E, Pellizzer A, Wang Y, Piazzesi A, Gentile D, Siddig S, Stork M, Hopkins CE, Händler K, Weis J, Roos A, Schultze JL, Nicotera P, Ehninger D, Bano D. Jackson J, et al. Among authors: hopkins ce. Mol Metab. 2022 Jul;61:101503. doi: 10.1016/j.molmet.2022.101503. Epub 2022 Apr 19. Mol Metab. 2022. PMID: 35452878 Free PMC article.
73 results