Hou C - Search Results

1

Structural Insight into the DNA Binding Function of Transcription Factor ERF.

Hou C, McCown C, Ivanov DN, Tsodikov OV. Hou C, et al. Biochemistry. 2020 Nov 11:10.1021/acs.biochem.0c00774. doi: 10.1021/acs.biochem.0c00774. Online ahead of print. Biochemistry. 2020. PMID: 33175491 Free PMC article.

2

Structural insight into MtmC, a bifunctional ketoreductase-methyltransferase involved in the assembly of the mithramycin trisaccharide chain.

Chen JM, Hou C, Wang G, Tsodikov OV, Rohr J. Chen JM, et al. Among authors: hou c. Biochemistry. 2015 Apr 21;54(15):2481-9. doi: 10.1021/bi501462g. Epub 2015 Apr 7. Biochemistry. 2015. PMID: 25587924 Free PMC article.

3

Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution.

Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S. Tsodikov OV, et al. Among authors: hou c. BMC Struct Biol. 2015 Jul 15;15:13. doi: 10.1186/s12900-015-0040-6. BMC Struct Biol. 2015. PMID: 26170207 Free PMC article.

4

Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1.

Hou C, Tsodikov OV. Hou C, et al. Biochemistry. 2015 Dec 22;54(50):7365-74. doi: 10.1021/acs.biochem.5b01121. Epub 2015 Dec 10. Biochemistry. 2015. PMID: 26618620

5

Dimerization and DNA recognition rules of mithramycin and its analogues.

Weidenbach S, Hou C, Chen JM, Tsodikov OV, Rohr J. Weidenbach S, et al. Among authors: hou c. J Inorg Biochem. 2016 Mar;156:40-7. doi: 10.1016/j.jinorgbio.2015.12.011. Epub 2015 Dec 18. J Inorg Biochem. 2016. PMID: 26760230 Free PMC article.

6

Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.

Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Willby MJ, et al. Among authors: hou c. ACS Chem Biol. 2016 Jun 17;11(6):1639-46. doi: 10.1021/acschembio.6b00110. Epub 2016 Apr 7. ACS Chem Biol. 2016. PMID: 27010218 Free PMC article.

7

Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.

Hou C, Weidenbach S, Cano KE, Wang Z, Mitra P, Ivanov DN, Rohr J, Tsodikov OV. Hou C, et al. Nucleic Acids Res. 2016 Oct 14;44(18):8990-9004. doi: 10.1093/nar/gkw761. Epub 2016 Sep 1. Nucleic Acids Res. 2016. PMID: 27587584 Free PMC article.

8

Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis.

Garzan A, Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Garzan A, et al. Among authors: hou c. J Med Chem. 2016 Dec 8;59(23):10619-10628. doi: 10.1021/acs.jmedchem.6b01161. Epub 2016 Nov 22. J Med Chem. 2016. PMID: 27933949 Free PMC article.

9

Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors.

Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Garzan A, et al. Among authors: hou c. ACS Infect Dis. 2017 Apr 14;3(4):302-309. doi: 10.1021/acsinfecdis.6b00193. Epub 2017 Feb 17. ACS Infect Dis. 2017. PMID: 28192916 Free PMC article.

10

Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.

Hou C, Biswas T, Tsodikov OV. Hou C, et al. Biochemistry. 2018 Apr 10;57(14):2084-2093. doi: 10.1021/acs.biochem.8b00036. Epub 2018 Mar 23. Biochemistry. 2018. PMID: 29558114

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