Hou TJ - Search Results

1

Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays.

Pang JP, Hu XP, Wang YX, Liao JN, Chai X, Wang XW, Shen C, Wang JJ, Zhang LL, Wang XY, Zhu F, Weng QJ, Xu L, Hou TJ, Li D. Pang JP, et al. Among authors: hou tj. Acta Pharmacol Sin. 2022 Sep;43(9):2429-2438. doi: 10.1038/s41401-021-00855-6. Epub 2022 Feb 2. Acta Pharmacol Sin. 2022. PMID: 35110698 Free PMC article.

2

Exploring the molecular basis of RNA recognition by the dimeric RNA-binding protein via molecular simulation methods.

Chang S, Zhang DW, Xu L, Wan H, Hou TJ, Kong R. Chang S, et al. Among authors: hou tj. RNA Biol. 2016 Nov;13(11):1133-1143. doi: 10.1080/15476286.2016.1223007. Epub 2016 Sep 3. RNA Biol. 2016. PMID: 27592836 Free PMC article.

3

Exploring the RNA-bound and RNA-free human Argonaute-2 by molecular dynamics simulation method.

Kong R, Xu L, Piao L, Zhang D, Hou TJ, Chang S. Kong R, et al. Among authors: hou tj. Chem Biol Drug Des. 2017 Nov;90(5):753-763. doi: 10.1111/cbdd.12997. Epub 2017 May 12. Chem Biol Drug Des. 2017. PMID: 28388001

4

Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.

Satheeshkumar R, Zhu R, Feng B, Huang C, Gao Y, Gao LX, Shen C, Hou TJ, Xu L, Li J, Zhu YL, Zhou YB, Wang WL. Satheeshkumar R, et al. Among authors: hou tj. Bioorg Med Chem Lett. 2020 Jun 1;30(11):127170. doi: 10.1016/j.bmcl.2020.127170. Epub 2020 Apr 3. Bioorg Med Chem Lett. 2020. PMID: 32273218

5

Improving Docking-Based Virtual Screening Ability by Integrating Multiple Energy Auxiliary Terms from Molecular Docking Scoring.

Ye WL, Shen C, Xiong GL, Ding JJ, Lu AP, Hou TJ, Cao DS. Ye WL, et al. Among authors: hou tj. J Chem Inf Model. 2020 Sep 28;60(9):4216-4230. doi: 10.1021/acs.jcim.9b00977. Epub 2020 May 11. J Chem Inf Model. 2020. PMID: 32352294

6

Discovery of novel antagonists targeting the DNA binding domain of androgen receptor by integrated docking-based virtual screening and bioassays.

Pang JP, Shen C, Zhou WF, Wang YX, Shan LH, Chai X, Shao Y, Hu XP, Zhu F, Zhu DY, Xiao L, Xu L, Xu XH, Li D, Hou TJ. Pang JP, et al. Among authors: hou tj. Acta Pharmacol Sin. 2022 Jan;43(1):229-239. doi: 10.1038/s41401-021-00632-5. Epub 2021 Mar 25. Acta Pharmacol Sin. 2022. PMID: 33767381 Free PMC article.

7

Discovery of novel MIF inhibitors that attenuate microglial inflammatory activation by structures-based virtual screening and in vitro bioassays.

Zhang Y, Xu L, Zhang Y, Pan J, Wang PQ, Tian S, Li HT, Gao BW, Hou TJ, Zhen XC, Zheng LT. Zhang Y, et al. Among authors: hou tj. Acta Pharmacol Sin. 2022 Jun;43(6):1508-1520. doi: 10.1038/s41401-021-00753-x. Epub 2021 Aug 24. Acta Pharmacol Sin. 2022. PMID: 34429524 Free PMC article.

8

Discovery of novel DprE1 inhibitors via computational bioactivity fingerprints and structure-based virtual screening.

Hu XP, Yang L, Chai X, Lei YX, Alam MS, Liu L, Shen C, Jiang DJ, Wang Z, Liu ZY, Xu L, Wan KL, Zhang TY, Yin YL, Li D, Cao DS, Hou TJ. Hu XP, et al. Among authors: hou tj. Acta Pharmacol Sin. 2022 Jun;43(6):1605-1615. doi: 10.1038/s41401-021-00779-1. Epub 2021 Oct 19. Acta Pharmacol Sin. 2022. PMID: 34667293 Free PMC article.

9

Novel Caspase-1 inhibitor CZL80 improves neurological function in mice after progressive ischemic stroke within a long therapeutic time-window.

Pan L, Tang WD, Wang K, Fang QF, Liu MR, Wu ZX, Wang Y, Cui SL, Hu G, Hou TJ, Hu WW, Chen Z, Zhang XN. Pan L, et al. Among authors: hou tj. Acta Pharmacol Sin. 2022 Nov;43(11):2817-2827. doi: 10.1038/s41401-022-00913-7. Epub 2022 May 2. Acta Pharmacol Sin. 2022. PMID: 35501362 Free PMC article.

10

CovInter: interaction data between coronavirus RNAs and host proteins.

Amahong K, Zhang W, Zhou Y, Zhang S, Yin J, Li F, Xu H, Yan T, Yue Z, Liu Y, Hou T, Qiu Y, Tao L, Han L, Zhu F. Amahong K, et al. Nucleic Acids Res. 2023 Jan 6;51(D1):D546-D556. doi: 10.1093/nar/gkac834. Nucleic Acids Res. 2023. PMID: 36200814 Free PMC article.

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