Houk KN - Search Results

1

Biocatalytic trifluoromethylation of unprotected phenols.

Simon RC, Busto E, Richter N, Resch V, Houk KN, Kroutil W. Simon RC, et al. Among authors: houk kn. Nat Commun. 2016 Nov 11;7:13323. doi: 10.1038/ncomms13323. Nat Commun. 2016. PMID: 27834376 Free PMC article.

2

Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism.

Yuan C, Liang Y, Hernandez T, Berriochoa A, Houk KN, Siegel D. Yuan C, et al. Among authors: houk kn. Nature. 2013 Jul 11;499(7457):192-6. doi: 10.1038/nature12284. Nature. 2013. PMID: 23846658

3

Conversion of amides to esters by the nickel-catalysed activation of amide C-N bonds.

Hie L, Fine Nathel NF, Shah TK, Baker EL, Hong X, Yang YF, Liu P, Houk KN, Garg NK. Hie L, et al. Among authors: houk kn. Nature. 2015 Aug 6;524(7563):79-83. doi: 10.1038/nature14615. Epub 2015 Jul 22. Nature. 2015. PMID: 26200342 Free PMC article.

4

Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions.

Eger E, Simon A, Sharma M, Yang S, Breukelaar WB, Grogan G, Houk KN, Kroutil W. Eger E, et al. Among authors: houk kn. J Am Chem Soc. 2020 Jan 15;142(2):792-800. doi: 10.1021/jacs.9b08704. Epub 2020 Jan 7. J Am Chem Soc. 2020. PMID: 31909617 Free PMC article.

5

Arene C-H borylation strategy enabled by a non-classical boron cluster-based electrophile.

Kim S, Treacy JW, Nelson YA, Gonzalez JAM, Gembicky M, Houk KN, Spokoyny AM. Kim S, et al. Among authors: houk kn. Nat Commun. 2023 Mar 25;14(1):1671. doi: 10.1038/s41467-023-37258-6. Nat Commun. 2023. PMID: 36966132 Free PMC article.

6

SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis.

Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN, Tang Y. Ohashi M, et al. Among authors: houk kn. Nature. 2017 Sep 28;549(7673):502-506. doi: 10.1038/nature23882. Epub 2017 Sep 13. Nature. 2017. PMID: 28902839 Free PMC article.

7

Biosynthesis of thiocarboxylic acid-containing natural products.

Dong LB, Rudolf JD, Kang D, Wang N, He CQ, Deng Y, Huang Y, Houk KN, Duan Y, Shen B. Dong LB, et al. Among authors: houk kn. Nat Commun. 2018 Jun 18;9(1):2362. doi: 10.1038/s41467-018-04747-y. Nat Commun. 2018. PMID: 29915173 Free PMC article.

8

A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.

Mallinson SJB, Machovina MM, Silveira RL, Garcia-Borràs M, Gallup N, Johnson CW, Allen MD, Skaf MS, Crowley MF, Neidle EL, Houk KN, Beckham GT, DuBois JL, McGeehan JE. Mallinson SJB, et al. Among authors: houk kn. Nat Commun. 2018 Jun 27;9(1):2487. doi: 10.1038/s41467-018-04878-2. Nat Commun. 2018. PMID: 29950589 Free PMC article.

9

Enzymatic one-step ring contraction for quinolone biosynthesis.

Kishimoto S, Hara K, Hashimoto H, Hirayama Y, Champagne PA, Houk KN, Tang Y, Watanabe K. Kishimoto S, et al. Among authors: houk kn. Nat Commun. 2018 Jul 19;9(1):2826. doi: 10.1038/s41467-018-05221-5. Nat Commun. 2018. PMID: 30026518 Free PMC article.

10

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons.

Huang X, Garcia-Borràs M, Miao K, Kan SBJ, Zutshi A, Houk KN, Arnold FH. Huang X, et al. Among authors: houk kn. ACS Cent Sci. 2019 Feb 27;5(2):270-276. doi: 10.1021/acscentsci.8b00679. Epub 2019 Feb 1. ACS Cent Sci. 2019. PMID: 30834315 Free PMC article.

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