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GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models.
Horder J, Andersson M, Mendez MA, Singh N, Tangen Ä, Lundberg J, Gee A, Halldin C, Veronese M, Bölte S, Farde L, Sementa T, Cash D, Higgins K, Spain D, Turkheimer F, Mick I, Selvaraj S, Nutt DJ, Lingford-Hughes A, Howes OD, Murphy DG, Borg J. Horder J, et al. Among authors: howes od. Sci Transl Med. 2018 Oct 3;10(461):eaam8434. doi: 10.1126/scitranslmed.aam8434. Sci Transl Med. 2018. PMID: 30282698 Free article.
Presynaptic 5-HT1A is related to 5-HTT receptor density in the human brain.
Bose SK, Mehta MA, Selvaraj S, Howes OD, Hinz R, Rabiner EA, Grasby PM, Turkheimer FE, Murthy V. Bose SK, et al. Among authors: howes od. Neuropsychopharmacology. 2011 Oct;36(11):2258-65. doi: 10.1038/npp.2011.113. Epub 2011 Jul 13. Neuropsychopharmacology. 2011. PMID: 21750580 Free PMC article.
Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship.
Kim E, Howes OD, Kim BH, Jeong JM, Lee JS, Jang IJ, Shin SG, Turkheimer FE, Kapur S, Kwon JS. Kim E, et al. Among authors: howes od. J Cereb Blood Flow Metab. 2012 Apr;32(4):759-68. doi: 10.1038/jcbfm.2011.180. Epub 2011 Dec 21. J Cereb Blood Flow Metab. 2012. PMID: 22186667 Free PMC article. Clinical Trial.
439 results