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Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1.
Howson LJ, Awad W, von Borstel A, Lim HJ, McWilliam HEG, Sandoval-Romero ML, Majumdar S, Hamzeh AR, Andrews TD, McDermott DH, Murphy PM, Le Nours J, Mak JYW, Liu L, Fairlie DP, McCluskey J, Villadangos JA, Cook MC, Turner SJ, Davey MS, Ojaimi S, Rossjohn J. Howson LJ, et al. Sci Immunol. 2020 Jul 24;5(49):eabc9492. doi: 10.1126/sciimmunol.abc9492. Sci Immunol. 2020. PMID: 32709702 Free PMC article.
Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor.
Rice MT, von Borstel A, Chevour P, Awad W, Howson LJ, Littler DR, Gherardin NA, Le Nours J, Giles EM, Berry R, Godfrey DI, Davey MS, Rossjohn J, Gully BS. Rice MT, et al. Among authors: howson lj. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2110288118. doi: 10.1073/pnas.2110288118. Proc Natl Acad Sci U S A. 2021. PMID: 34845016 Free PMC article.
Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire.
von Borstel A, Chevour P, Arsovski D, Krol JMM, Howson LJ, Berry AA, Day CL, Ogongo P, Ernst JD, Nomicos EYH, Boddey JA, Giles EM, Rossjohn J, Traore B, Lyke KE, Williamson KC, Crompton PD, Davey MS. von Borstel A, et al. Among authors: howson lj. Sci Transl Med. 2021 Dec;13(622):eabe7430. doi: 10.1126/scitranslmed.abe7430. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851691 Free PMC article.
Diverse Streptococcus pneumoniae Strains Drive a Mucosal-Associated Invariant T-Cell Response Through Major Histocompatibility Complex class I-Related Molecule-Dependent and Cytokine-Driven Pathways.
Kurioka A, van Wilgenburg B, Javan RR, Hoyle R, van Tonder AJ, Harrold CL, Leng T, Howson LJ, Shepherd D, Cerundolo V, Brueggemann AB, Klenerman P. Kurioka A, et al. Among authors: howson lj. J Infect Dis. 2018 Mar 5;217(6):988-999. doi: 10.1093/infdis/jix647. J Infect Dis. 2018. PMID: 29267892 Free PMC article.
Case Report: Cytomegalovirus Disease Is an Under-Recognized Contributor to Morbidity and Mortality in Common Variable Immunodeficiency.
Chan S, Godsell J, Horton M, Farchione A, Howson LJ, Margetts M, Jin C, Chatelier J, Yong M, Sasadeusz J, Douglass JA, Slade CA, Bryant VL. Chan S, et al. Among authors: howson lj. Front Immunol. 2022 Feb 15;13:815193. doi: 10.3389/fimmu.2022.815193. eCollection 2022. Front Immunol. 2022. PMID: 35242131 Free PMC article.
Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.
Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V. Napolitani G, et al. Nat Immunol. 2019 Apr;20(4):514. doi: 10.1038/s41590-019-0357-6. Nat Immunol. 2019. PMID: 30862955
17 results