Hreniuk DL - Search Results

1

Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a.

Bednarek MA, Feighner SD, Pong SS, McKee KK, Hreniuk DL, Silva MV, Warren VA, Howard AD, Van Der Ploeg LH, Heck JV. Bednarek MA, et al. Among authors: hreniuk dl. J Med Chem. 2000 Nov 16;43(23):4370-6. doi: 10.1021/jm0001727. J Med Chem. 2000. PMID: 11087562

2

Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.

Bednarek MA, Tan C, Hreniuk DL, Palyha OC, MacNeil DJ, Van Der Ploeg LH, Howard AD, Feighner SD. Bednarek MA, et al. Among authors: hreniuk dl. J Biol Chem. 2002 Apr 19;277(16):13821-6. doi: 10.1074/jbc.M200563200. Epub 2002 Feb 11. J Biol Chem. 2002. PMID: 11839762 Free article.

3

Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.

Bednarek MA, Hreniuk DL, Tan C, Palyha OC, MacNeil DJ, Van der Ploeg LH, Howard AD, Feighner SD. Bednarek MA, et al. Among authors: hreniuk dl. Biochemistry. 2002 May 21;41(20):6383-90. doi: 10.1021/bi0200514. Biochemistry. 2002. PMID: 12009900

4

4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.

Jiang J, Lin P, Hoang M, Chang L, Tan C, Feighner S, Palyha OC, Hreniuk DL, Pan J, Sailer AW, Morin NR, MacNeil DJ, Howard AD, Van der Ploeg LH, Goulet MT, DeVita RJ. Jiang J, et al. Among authors: hreniuk dl. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5275-9. doi: 10.1016/j.bmcl.2006.08.008. Epub 2006 Aug 17. Bioorg Med Chem Lett. 2006. PMID: 16919453

5

Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists.

Pasternak A, Goble SD, deJesus RK, Hreniuk DL, Chung CC, Tota MR, Mazur P, Feighner SD, Howard AD, Mills SG, Yang L. Pasternak A, et al. Among authors: hreniuk dl. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6237-40. doi: 10.1016/j.bmcl.2009.08.076. Epub 2009 Aug 26. Bioorg Med Chem Lett. 2009. PMID: 19767208

6

A receptor in pituitary and hypothalamus that functions in growth hormone release.

Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH. Howard AD, et al. Among authors: hreniuk dl. Science. 1996 Aug 16;273(5277):974-7. doi: 10.1126/science.273.5277.974. Science. 1996. PMID: 8688086

7

Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.

McKee KK, Palyha OC, Feighner SD, Hreniuk DL, Tan CP, Phillips MS, Smith RG, Van der Ploeg LH, Howard AD. McKee KK, et al. Among authors: hreniuk dl. Mol Endocrinol. 1997 Apr;11(4):415-23. doi: 10.1210/mend.11.4.9908. Mol Endocrinol. 1997. PMID: 9092793

8

Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.

Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, Underwood D, Tata JR, Dean DC, Tan CP, McKee KK, Woods JW, Patchett AA, Smith RG, Van der Ploeg LH. Feighner SD, et al. Among authors: hreniuk dl. Mol Endocrinol. 1998 Jan;12(1):137-45. doi: 10.1210/mend.12.1.0051. Mol Endocrinol. 1998. PMID: 9440817

9

Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors.

McKee KK, Tan CP, Palyha OC, Liu J, Feighner SD, Hreniuk DL, Smith RG, Howard AD, Van der Ploeg LH. McKee KK, et al. Among authors: hreniuk dl. Genomics. 1997 Dec 15;46(3):426-34. doi: 10.1006/geno.1997.5069. Genomics. 1997. PMID: 9441746

10

Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors.

Tan CP, McKee KK, Liu Q, Palyha OC, Feighner SD, Hreniuk DL, Smith RG, Howard AD. Tan CP, et al. Among authors: hreniuk dl. Genomics. 1998 Sep 1;52(2):223-9. doi: 10.1006/geno.1998.5441. Genomics. 1998. PMID: 9782091

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