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Intermittent Preventive Treatment for Malaria in Pregnancy: Optimization of Target Concentrations of Dihydroartemisinin-Piperaquine.
Savic RM, Jagannathan P, Kajubi R, Huang L, Zhang N, Were M, Kakuru A, Muhindo MK, Mwebaza N, Wallender E, Clark TD, Opira B, Kamya M, Havlir DV, Rosenthal PJ, Dorsey G, Aweeka FT. Savic RM, et al. Among authors: huang l. Clin Infect Dis. 2018 Sep 14;67(7):1079-1088. doi: 10.1093/cid/ciy218. Clin Infect Dis. 2018. PMID: 29547881 Free PMC article. Clinical Trial.
In vitro metabolism of piperaquine is primarily mediated by CYP3A4.
Lee TM, Huang L, Johnson MK, Lizak P, Kroetz D, Aweeka F, Parikh S. Lee TM, et al. Among authors: huang l. Xenobiotica. 2012 Nov;42(11):1088-95. doi: 10.3109/00498254.2012.693972. Epub 2012 Jun 6. Xenobiotica. 2012. PMID: 22671777 Free PMC article.
Nevirapine inhibits the anti-HIV activity of CD8+ cells.
Liu L, Wang L, Huang L, Siu V, Teque F, Aweeka FT, Levy JA. Liu L, et al. Among authors: huang l. J Acquir Immune Defic Syndr. 2013 Jun 1;63(2):184-8. doi: 10.1097/QAI.0b013e318289822d. J Acquir Immune Defic Syndr. 2013. PMID: 23392464 Free PMC article.
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