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Double superhelix model of high density lipoprotein.
Wu Z, Gogonea V, Lee X, Wagner MA, Li XM, Huang Y, Undurti A, May RP, Haertlein M, Moulin M, Gutsche I, Zaccai G, DiDonato JA, Hazen SL. Wu Z, et al. Among authors: huang y. J Biol Chem. 2009 Dec 25;284(52):36605-36619. doi: 10.1074/jbc.M109.039537. Epub 2009 Oct 7. J Biol Chem. 2009. PMID: 19812036 Free PMC article.
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex.
Huang Y, Wu Z, Riwanto M, Gao S, Levison BS, Gu X, Fu X, Wagner MA, Besler C, Gerstenecker G, Zhang R, Li XM, DiDonato AJ, Gogonea V, Tang WH, Smith JD, Plow EF, Fox PL, Shih DM, Lusis AJ, Fisher EA, DiDonato JA, Landmesser U, Hazen SL. Huang Y, et al. J Clin Invest. 2013 Sep;123(9):3815-28. doi: 10.1172/JCI67478. Epub 2013 Aug 1. J Clin Invest. 2013. PMID: 23908111 Free PMC article.
Effects of native and myeloperoxidase-modified apolipoprotein a-I on reverse cholesterol transport and atherosclerosis in mice.
Hewing B, Parathath S, Barrett T, Chung WK, Astudillo YM, Hamada T, Ramkhelawon B, Tallant TC, Yusufishaq MS, Didonato JA, Huang Y, Buffa J, Berisha SZ, Smith JD, Hazen SL, Fisher EA. Hewing B, et al. Among authors: huang y. Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):779-89. doi: 10.1161/ATVBAHA.113.303044. Epub 2014 Jan 9. Arterioscler Thromb Vasc Biol. 2014. PMID: 24407029 Free PMC article.
Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional.
DiDonato JA, Aulak K, Huang Y, Wagner M, Gerstenecker G, Topbas C, Gogonea V, DiDonato AJ, Tang WHW, Mehl RA, Fox PL, Plow EF, Smith JD, Fisher EA, Hazen SL. DiDonato JA, et al. Among authors: huang y. J Biol Chem. 2014 Apr 11;289(15):10276-10292. doi: 10.1074/jbc.M114.556506. Epub 2014 Feb 20. J Biol Chem. 2014. PMID: 24558038 Free PMC article.
Identification of Critical Paraoxonase 1 Residues Involved in High Density Lipoprotein Interaction.
Gu X, Huang Y, Levison BS, Gerstenecker G, DiDonato AJ, Hazen LB, Lee J, Gogonea V, DiDonato JA, Hazen SL. Gu X, et al. Among authors: huang y. J Biol Chem. 2016 Jan 22;291(4):1890-1904. doi: 10.1074/jbc.M115.678334. Epub 2015 Nov 13. J Biol Chem. 2016. PMID: 26567339 Free PMC article.
We recently showed that PON1, myeloperoxidase, and HDL bind to one another in vivo forming a functional ternary complex (Huang, Y., Wu, Z., Riwanto, M., Gao, S., Levison, B. S., Gu, X., Fu, X., Wagner, M. ...
We recently showed that PON1, myeloperoxidase, and HDL bind to one another in vivo forming a functional ternary complex (Huang, Y …
A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein.
Gu X, Wu Z, Huang Y, Wagner MA, Baleanu-Gogonea C, Mehl RA, Buffa JA, DiDonato AJ, Hazen LB, Fox PL, Gogonea V, Parks JS, DiDonato JA, Hazen SL. Gu X, et al. Among authors: huang y. J Biol Chem. 2016 Mar 18;291(12):6386-95. doi: 10.1074/jbc.M115.696088. Epub 2016 Jan 21. J Biol Chem. 2016. PMID: 26797122 Free PMC article.
Site-specific 5-hydroxytryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high-density lipoprotein biogenesis.
Zamanian-Daryoush M, Gogonea V, DiDonato AJ, Buffa JA, Choucair I, Levison BS, Hughes RA, Ellington AD, Huang Y, Li XS, DiDonato JA, Hazen SL. Zamanian-Daryoush M, et al. Among authors: huang y. J Biol Chem. 2020 Apr 10;295(15):4836-4848. doi: 10.1074/jbc.RA119.012092. Epub 2020 Feb 25. J Biol Chem. 2020. PMID: 32098873 Free PMC article.
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