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Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Pumroy RA, Samanta A, Liu Y, Hughes TE, Zhao S, Yudin Y, Rohacs T, Han S, Moiseenkova-Bell VY. Pumroy RA, et al. Among authors: hughes te. Elife. 2019 Sep 30;8:e48792. doi: 10.7554/eLife.48792. Elife. 2019. PMID: 31566564 Free PMC article.
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. Hughes TET, et al. Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323279 Free PMC article.
Structural insights on TRPV5 gating by endogenous modulators.
Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY. Hughes TET, et al. Nat Commun. 2018 Oct 10;9(1):4198. doi: 10.1038/s41467-018-06753-6. Nat Commun. 2018. PMID: 30305626 Free PMC article.
Structure-based characterization of novel TRPV5 inhibitors.
Hughes TE, Del Rosario JS, Kapoor A, Yazici AT, Yudin Y, Fluck EC 3rd, Filizola M, Rohacs T, Moiseenkova-Bell VY. Hughes TE, et al. Elife. 2019 Oct 25;8:e49572. doi: 10.7554/eLife.49572. Elife. 2019. PMID: 31647410 Free PMC article.
Cryo Electron Microscopy of TRP Channels.
Samanta A, Hughes TET, Moiseenkova-Bell VY. Samanta A, et al. Methods Mol Biol. 2019;1987:39-50. doi: 10.1007/978-1-4939-9446-5_3. Methods Mol Biol. 2019. PMID: 31028672 Free PMC article.
Transient Receptor Potential (TRP) Channels.
Samanta A, Hughes TET, Moiseenkova-Bell VY. Samanta A, et al. Subcell Biochem. 2018;87:141-165. doi: 10.1007/978-981-10-7757-9_6. Subcell Biochem. 2018. PMID: 29464560 Free PMC article. Review.
Cryo-EM structure of 5-HT3A receptor in its resting conformation.
Basak S, Gicheru Y, Samanta A, Molugu SK, Huang W, Fuente M, Hughes T, Taylor DJ, Nieman MT, Moiseenkova-Bell V, Chakrapani S. Basak S, et al. Nat Commun. 2018 Feb 6;9(1):514. doi: 10.1038/s41467-018-02997-4. Nat Commun. 2018. PMID: 29410406 Free PMC article.
193 results