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Year Number of Results
2001 1
2005 2
2006 1
2007 7
2008 3
2009 4
2010 5
2011 4
2012 9
2013 7
2014 13
2015 14
2016 9
2017 3
2018 7
2019 3
2020 4
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2023 3
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111 results

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Page 1
E3 ubiquitin ligase Casitas B lineage lymphoma-b and its potential therapeutic implications for immunotherapy.
Jafari D, Mousavi MJ, Keshavarz Shahbaz S, Jafarzadeh L, Tahmasebi S, Spoor J, Esmaeilzadeh A. Jafari D, et al. Clin Exp Immunol. 2021 Apr;204(1):14-31. doi: 10.1111/cei.13560. Epub 2021 Jan 10. Clin Exp Immunol. 2021. PMID: 33306199 Free PMC article. Review.
Maintaining the balance between immunity and tolerance of immune cells is strongly controlled by several sophisticated regulatory mechanisms of the immune system. Among these, the E3 ligase ubiquitin Casitas B cell lymphoma-b (Cbl-b) is a newly identified component …
Maintaining the balance between immunity and tolerance of immune cells is strongly controlled by several sophisticated regulatory mechanisms …
HYPK coordinates degradation of polyneddylated proteins by autophagy.
Ghosh DK, Ranjan A. Ghosh DK, et al. Autophagy. 2022 Aug;18(8):1763-1784. doi: 10.1080/15548627.2021.1997053. Epub 2021 Nov 26. Autophagy. 2022. PMID: 34836490 Free PMC article.
Thus, we propose an indispensable and additive role of neddylation and HYPK in clearance of protein aggregates by autophagy, resulting in cytoprotective effect during proteotoxic stress.Abbreviations: ATG5, autophagy related 5; ATG12, autophagy related 12; ATG14, autophagy relate …
Thus, we propose an indispensable and additive role of neddylation and HYPK in clearance of protein aggregates by autophagy, resulting in cy …
Sinularamides A-G, Terpenoid-Derived Spermidine and Spermine Conjugates with Casitas B-Lineage Lymphoma Proto-Oncogene B (Cbl-b) Inhibitory Activities from a Sinularia sp. Soft Coral.
Jiang W, Wang D, Wilson BAP, Voeller D, Bokesch HR, Smith EA, Lipkowitz S, O'Keefe BR, Gustafson KR. Jiang W, et al. J Nat Prod. 2021 Jun 25;84(6):1831-1837. doi: 10.1021/acs.jnatprod.1c00367. Epub 2021 May 26. J Nat Prod. 2021. PMID: 34038132 Free PMC article.
An extract of a Sinularia sp. soft coral showed inhibitory activity against the E3-ubiquitin ligase casitas B-lineage lymphoma proto-oncogene B (Cbl-b). Subsequent bioassay-guided separation of the extract provided a series of terpenoid-d …
An extract of a Sinularia sp. soft coral showed inhibitory activity against the E3-ubiquitin ligase casitas B-lineage …
c-Casitas b-Lineage Lymphoma Downregulation Improves the Ability of Long-term Cultured Mesenchymal Stem Cells for Promoting Angiogenesis and Diabetic Wound Healing.
Shen C, Lu Y, Zhang J, Li Y, Zhang Y, Fan D. Shen C, et al. Cell Transplant. 2021 Jan-Dec;30:963689721989605. doi: 10.1177/0963689721989605. Cell Transplant. 2021. PMID: 33588607 Free PMC article.
The repair function of mesenchymal stem cells (MSCs) impaired after long-term culture in vitro. Studies have shown that the proto-oncogene c-Casitas b-lineage lymphoma (c-Cbl) can regulate receptor- and non-receptor tyrosine kinase, which …
The repair function of mesenchymal stem cells (MSCs) impaired after long-term culture in vitro. Studies have shown that the proto- …
E3 ubiquitin ligase casitas B-lineage lymphoma-b modulates T-cell anergic resistance via phosphoinositide 3-kinase signaling in patients with immune thrombocytopenia.
Liu L, Xiang Y, Shao L, Yuan C, Song X, Sun M, Liu Y, Zhang X, Du S, Hou M, Peng J, Shi Y. Liu L, et al. J Thromb Haemost. 2024 Apr;22(4):1202-1214. doi: 10.1016/j.jtha.2023.12.032. Epub 2024 Jan 4. J Thromb Haemost. 2024. PMID: 38184203
BACKGROUND: The E3 ubiquitin ligase casitas B-lineage lymphoma-b (CBLB) is a newly identified component of the ubiquitin-dependent protein degradation system and is considered an important negative regulator of immune cells. ...
BACKGROUND: The E3 ubiquitin ligase casitas B-lineage lymphoma-b (CBLB) is a newly identified component of the u …
Casitas B lineage lymphoma b is a key regulator of peripheral tolerance in systemic lupus erythematosus.
Gómez-Martín D, Ibarra-Sánchez M, Romo-Tena J, Cruz-Ruíz J, Esparza-López J, Galindo-Campos M, Díaz-Zamudio M, Alcocer-Varela J. Gómez-Martín D, et al. Arthritis Rheum. 2013 Apr;65(4):1032-42. doi: 10.1002/art.37833. Arthritis Rheum. 2013. PMID: 23280105 Free article.
OBJECTIVE: To analyze whether the expression and modulation of T cell receptor (TCR) signaling is dependent on Casitas B lineage lymphoma b (Cbl-b) in T cells from patients with systemic lupus erythematosus (SLE) upon stimulation with a tolerogenic sub …
OBJECTIVE: To analyze whether the expression and modulation of T cell receptor (TCR) signaling is dependent on Casitas B li …
The effect of Casitas b-lineage lymphoma b on regulating T follicular helper in lupus nephritis.
Wu J, Lu WJ, Shan HZ, Zhang ZW, Cui SN, Chen LZ, Fu YY, Xiao Y. Wu J, et al. Eur Rev Med Pharmacol Sci. 2020 Apr;24(8):4451-4460. doi: 10.26355/eurrev_202004_21027. Eur Rev Med Pharmacol Sci. 2020. PMID: 32373983 Free article.
OBJECTIVE: The purpose of this study was to investigate the effect of Casitas b-lineage lymphoma b (Cblb) on the regulation of T follicular helper (Tfh) in the development of lupus nephritis. ...
OBJECTIVE: The purpose of this study was to investigate the effect of Casitas b-lineage lymphoma b (Cblb) on the …
Casitas B-lineage lymphoma mutants activate AKT to induce transformation in cooperation with class III receptor tyrosine kinases.
Polzer H, Janke H, Schmid D, Hiddemann W, Spiekermann K. Polzer H, et al. Exp Hematol. 2013 Mar;41(3):271-80.e4. doi: 10.1016/j.exphem.2012.10.016. Epub 2012 Nov 2. Exp Hematol. 2013. PMID: 23127761 Free article.
In this study, we show that an oncogenic mutant of the ubiquitin ligase casitas B-lineage lymphoma (CBL; CBLdeltaexon8), which is found in acute myeloid leukemia patients, predominantly cooperates with receptor tyrosine kinase (RTK) class III receptors …
In this study, we show that an oncogenic mutant of the ubiquitin ligase casitas B-lineage lymphoma (CBL; CBLdelt …
111 results