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Year Number of Results
1991 1
1993 2
1994 2
1995 2
1996 4
1997 3
1998 6
2000 4
2001 6
2002 2
2003 4
2004 4
2007 1
2008 3
2009 3
2010 2
2011 1
2012 1
2013 1
2014 2
2015 4
2016 3
2017 3
2018 4
2019 4
2020 4
2021 8
2022 5
2023 2
2024 1

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84 results

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Page 1
Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes.
ElFar OA, Billa N, Lim HR, Chew KW, Cheah WY, Munawaroh HSH, Balakrishnan D, Show PL. ElFar OA, et al. Bioengineered. 2022 Jun;13(6):14681-14718. doi: 10.1080/21655979.2022.2100863. Bioengineered. 2022. PMID: 35946342 Free PMC article. Review.
In addition, it will open doors for research in delivering active pharmaceutical ingredients (APIs) in femtoscale with the use of various existing and new formulations.Abbrevations: SDGs; Sustainable Development Goals, IL-4; Interleukin-4, HDL; High-De …
In addition, it will open doors for research in delivering active pharmaceutical ingredients (APIs) in femtoscale with the use of various ex …
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice.
de Alwis R, Gan ES, Chen S, Leong YS, Tan HC, Zhang SL, Yau C, Low JGH, Kalimuddin S, Matsuda D, Allen EC, Hartman P, Park KJ, Alayyoubi M, Bhaskaran H, Dukanovic A, Bao Y, Clemente B, Vega J, Roberts S, Gonzalez JA, Sablad M, Yelin R, Taylor W, Tachikawa K, Parker S, Karmali P, Davis J, Sullivan BM, Sullivan SM, Hughes SG, Chivukula P, Ooi EE. de Alwis R, et al. Mol Ther. 2021 Jun 2;29(6):1970-1983. doi: 10.1016/j.ymthe.2021.04.001. Epub 2021 Apr 5. Mol Ther. 2021. PMID: 33823303 Free PMC article.
Assaying for intracellular cytokine staining for interferon (IFN)gamma and interleukin-4 (IL-4)-positive CD4(+) T helper (Th) lymphocytes as well as anti-spike glycoprotein immunoglobulin G (IgG)2a/IgG1 ratios supported a strong Th1-dominant immune res …
Assaying for intracellular cytokine staining for interferon (IFN)gamma and interleukin-4 (IL-4)-positive CD4(+) …
Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin.
Jaguin M, Houlbert N, Fardel O, Lecureur V. Jaguin M, et al. Cell Immunol. 2013 Jan;281(1):51-61. doi: 10.1016/j.cellimm.2013.01.010. Epub 2013 Feb 4. Cell Immunol. 2013. PMID: 23454681
Phenotypic markers of mouse polarized Mphi have been extensively studied, whereas their human counterparts remain less characterized. The main goal of this study was therefore to carefully characterize phenotypic and genomic markers of primary human Mphi generated f …
Phenotypic markers of mouse polarized Mphi have been extensively studied, whereas their human counterparts remain less characterized. …
SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.
Bidault G, Virtue S, Petkevicius K, Jolin HE, Dugourd A, Guénantin AC, Leggat J, Mahler-Araujo B, Lam BYH, Ma MK, Dale M, Carobbio S, Kaser A, Fallon PG, Saez-Rodriguez J, McKenzie ANJ, Vidal-Puig A. Bidault G, et al. Nat Metab. 2021 Sep;3(9):1150-1162. doi: 10.1038/s42255-021-00440-5. Epub 2021 Sep 16. Nat Metab. 2021. PMID: 34531575 Free PMC article.
In this study, we show that the anabolic transcription factor sterol regulatory element binding protein 1 (SREBP1) is activated in response to the canonical T helper 2 cell cytokine interleukin-4 to trigger the de novo lipogenesis (DNL) programme, as a necessary ste …
In this study, we show that the anabolic transcription factor sterol regulatory element binding protein 1 (SREBP1) is activated in response …
Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.
Weinstock A, Rahman K, Yaacov O, Nishi H, Menon P, Nikain CA, Garabedian ML, Pena S, Akbar N, Sansbury BE, Heffron SP, Liu J, Marecki G, Fernandez D, Brown EJ, Ruggles KV, Ramsey SA, Giannarelli C, Spite M, Choudhury RP, Loke P, Fisher EA. Weinstock A, et al. Elife. 2021 Mar 15;10:e67932. doi: 10.7554/eLife.67932. Elife. 2021. PMID: 33720008 Free PMC article.
Using Il4(-/-)Il13(-/-) mice, resolution was impaired, and in control mice, in both progressing and resolving plaques, levels of IL-4 were stably low and IL-13 was undetectable. This suggested that IL-4 is required for atherosclerosis resolution, but c …
Using Il4(-/-)Il13(-/-) mice, resolution was impaired, and in control mice, in both progressing and resolving plaques, levels of IL- …
Engineered T Regulatory Type 1 Cells for Clinical Application.
Gregori S, Roncarolo MG. Gregori S, et al. Front Immunol. 2018 Feb 15;9:233. doi: 10.3389/fimmu.2018.00233. eCollection 2018. Front Immunol. 2018. PMID: 29497421 Free PMC article. Review.
Inducible T regulatory type 1 (Tr1) cells are characterized by the co-expression of CD49b and lymphocyte-activation gene 3 (LAG-3) and the ability to secrete IL-10, TGF-beta, and granzyme (Gz) B, in the absence of IL-4 and IL-17. The chief mechanisms by which Tr1 ce …
Inducible T regulatory type 1 (Tr1) cells are characterized by the co-expression of CD49b and lymphocyte-activation gene 3 (LAG-3) and the a …
Cytokine Gene Polymorphisms in Chinese Children with Idiopathic Nephrotic Syndrome.
Li W, Li L, He L, Du Y, Fu HD, Peng ZY, Xiang WQ, Mao JH. Li W, et al. Iran J Immunol. 2022 Mar;19(1):9. doi: 10.22034/IJI.2022.92367.2146. Iran J Immunol. 2022. PMID: 35293350 Free article.
RESULTS: Among 182 children with INS, 89 (48.6%) were steroid-sensitive (SS), 73 (39.9%) were steroid-dependent (SD) and 21 (11.5%) were steroid-resistant (SR). In 20 SNPs, IL-4-rs2243283 exhibited a significantly different genotype distribution between INS a …
RESULTS: Among 182 children with INS, 89 (48.6%) were steroid-sensitive (SS), 73 (39.9%) were steroid-dependent (SD) and 21 (11.5%) were ste …
Cytokines and the immune response.
Van der Meide PH, Schellekens H. Van der Meide PH, et al. Biotherapy. 1996;8(3-4):243-9. doi: 10.1007/BF01877210. Biotherapy. 1996. PMID: 8813336 Review.
The meeting in Budapest was focussed on cytokines known to contribute to the pathophysiology of autoimmune diseases, infectious diseases and allograft rejection (e.g., IL-1, IL-4, IL-6, IL-10, IL-12, TNF-alpha and IFN-alpha, -beta, -gamma). ...Treatment of R. aurant …
The meeting in Budapest was focussed on cytokines known to contribute to the pathophysiology of autoimmune diseases, infectious diseases and …
Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids.
Kam JC, Szefler SJ, Surs W, Sher ER, Leung DY. Kam JC, et al. J Immunol. 1993 Oct 1;151(7):3460-6. J Immunol. 1993. PMID: 8376786
These effects of IL-2 + IL-4 on PBMC GR affinity and response to MPN were blocked by co-incubation with IFN-gamma. ...The altered PBMC GR binding from patients with SR asthma reversed to normal when incubated with medium alone, but was sustained with IL-2 + …
These effects of IL-2 + IL-4 on PBMC GR affinity and response to MPN were blocked by co-incubation with IFN-gamma. ...The alte …
Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages.
Dobashi K, Aihara M, Araki T, Shimizu Y, Utsugi M, Iizuka K, Murata Y, Hamuro J, Nakazawa T, Mori M. Dobashi K, et al. Clin Exp Immunol. 2001 May;124(2):290-6. doi: 10.1046/j.1365-2249.2001.01535.x. Clin Exp Immunol. 2001. PMID: 11422207 Free PMC article.
Glutathione tripeptide regulates the intracellular redox status and other aspects of cell physiology. We examined whether IFN-gamma and IL-4 affect the balance between intracellular reduced glutathione (GSH) and oxidized (GSSG) glutathione, as this may affect IL-12 …
Glutathione tripeptide regulates the intracellular redox status and other aspects of cell physiology. We examined whether IFN-gamma and I …
84 results