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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 6
2004 19
2005 44
2006 59
2007 85
2008 138
2009 172
2010 299
2011 296
2012 385
2013 393
2014 343
2015 409
2016 428
2017 329
2018 356
2019 374
2020 313
2021 295
2022 255
2023 192
2024 70

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4,619 results

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Page 1
NANOG expression in human development and cancerogenesis.
Grubelnik G, Boštjančič E, Pavlič A, Kos M, Zidar N. Grubelnik G, et al. Exp Biol Med (Maywood). 2020 Mar;245(5):456-464. doi: 10.1177/1535370220905560. Epub 2020 Feb 10. Exp Biol Med (Maywood). 2020. PMID: 32041418 Free PMC article. Review.
NANOG is an important stem cell transcription factor involved in human development and cancerogenesis. ...Postnatally, NANOG is undetectable or expressed in very low amounts in the majority of human tissues. ...
NANOG is an important stem cell transcription factor involved in human development and cancerogenesis. ...Postnatally, NANO …
The clinicopathological and prognostic value of Nanog in human gastrointestinal luminal cancer: A meta-analysis.
Liang C, Zhao T, Ge H, Xu Y, Ren S, Yue C, Li G, Wu J. Liang C, et al. Int J Surg. 2018 May;53:193-200. doi: 10.1016/j.ijsu.2018.03.050. Epub 2018 Mar 28. Int J Surg. 2018. PMID: 29602014 Free article. Review.
However, the clinicopathological and prognostic role of Nanog in gastrointestinal luminal cancer remains controversial. Therefore, we conducted a meta-analysis to assess the role of Nanog in gastrointestinal luminal cancer. ...CONCLUSION: The pooled results suggeste …
However, the clinicopathological and prognostic role of Nanog in gastrointestinal luminal cancer remains controversial. Therefore, we …
Core transcriptional regulatory circuitry in human embryonic stem cells.
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA. Boyer LA, et al. Cell. 2005 Sep 23;122(6):947-56. doi: 10.1016/j.cell.2005.08.020. Cell. 2005. PMID: 16153702 Free PMC article.
To gain insights into transcriptional regulation of human ES cells, we have identified OCT4, SOX2, and NANOG target genes using genome-scale location analysis. ...Our data also indicate that OCT4, SOX2, and NANOG collaborate to form regulatory circuitry consi …
To gain insights into transcriptional regulation of human ES cells, we have identified OCT4, SOX2, and NANOG target genes usin …
Regulation of NANOG in cancer cells.
Gong S, Li Q, Jeter CR, Fan Q, Tang DG, Liu B. Gong S, et al. Mol Carcinog. 2015 Sep;54(9):679-87. doi: 10.1002/mc.22340. Epub 2015 May 27. Mol Carcinog. 2015. PMID: 26013997 Free PMC article. Review.
Therefore, NANOG expression determines the cell fate not only in pluripotent cells but also in cancer cells. Although the regulation of NANOG in normal embryonic stem cells is reasonably well understood, the regulation of NANOG in cancer cells has only emerge …
Therefore, NANOG expression determines the cell fate not only in pluripotent cells but also in cancer cells. Although the regulation …
Nanog suppression enhanced the chemosensitivity of human non-small-cell lung cancer cells to Cisplatin and inhibited cell migration.
Najafzadeh B, Motafakkerazad R, Najafi S, Amini M, Alemohammad H, Vasefifar P, Baradaran B. Najafzadeh B, et al. Pathol Res Pract. 2022 May;233:153869. doi: 10.1016/j.prp.2022.153869. Epub 2022 Apr 1. Pathol Res Pract. 2022. PMID: 35398618
Then, A549 lung cancer cells were transfected with Nanog siRNA and treated with Cisplatin individually or combined. ...Consistently, Nanog suppression combined with Cisplatin led to upregulation of Caspase-3 apoptotic gene and Bax/Bcl-2 ratio. ...
Then, A549 lung cancer cells were transfected with Nanog siRNA and treated with Cisplatin individually or combined. ...Consistently, …
Nanog maintains human chondrocyte phenotype and function in vitro.
Zheng H, Gourronc F, Buckwalter JA, Martin JA. Zheng H, et al. J Orthop Res. 2010 Apr;28(4):516-21. doi: 10.1002/jor.20989. J Orthop Res. 2010. PMID: 19834952 Free article.
We hypothesized that Nanog could stabilize the phenotype of cultured human chondrocytes in long-term monolayer cultures. To test this hypothesis, the human Nanog gene was stably transduced into human chondrocytes using a retroviral vector. ...
We hypothesized that Nanog could stabilize the phenotype of cultured human chondrocytes in long-term monolayer cultures. To te …
Epithelium-specific ETS transcription factor-1 regulates NANOG expression and inhibits NANOG-induced proliferation of human embryonic carcinoma cells.
Park SW, Do HJ, Choi W, Lim DS, Park KH, Kim JH. Park SW, et al. Biochimie. 2021 Jul;186:33-42. doi: 10.1016/j.biochi.2021.04.004. Epub 2021 Apr 15. Biochimie. 2021. PMID: 33865902
In this study, we investigated how ESE-1 influences NANOG expression and NANOG-induced proliferation in human germ cell-derived embryonic carcinoma NCCIT cells. ...Site-directed mutagenesis of the putative EBS abrogated the repressive effect of ESE-1 on NA …
In this study, we investigated how ESE-1 influences NANOG expression and NANOG-induced proliferation in human germ cell …
Pin1-Nanog expression in human glioma is correlated with advanced tumor progression.
Yang Y, Niu CS, Cheng CD. Yang Y, et al. Oncol Rep. 2013 Aug;30(2):560-6. doi: 10.3892/or.2013.2481. Epub 2013 May 23. Oncol Rep. 2013. PMID: 23708493 Free PMC article.
The present study investigated the expression and relationship of Pin1 and Nanog in human gliomas. Significantly higher mRNA and protein expression levels of Pin1 and Nanog were demonstrated in 120 glioma specimens of different pathological grades by RT-PCR, …
The present study investigated the expression and relationship of Pin1 and Nanog in human gliomas. Significantly higher mRNA a …
Emerging role of nanog in tumorigenesis and cancer stem cells.
Iv Santaliz-Ruiz LE, Xie X, Old M, Teknos TN, Pan Q. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8. doi: 10.1002/ijc.28690. Epub 2014 Jan 13. Int J Cancer. 2014. PMID: 24375318 Free PMC article. Review.
Elevated Nanog is associated with poorer outcome in numerous epithelial malignancies. Nanog is enriched in CSCs and ablation of Nanog is sufficient to reduce the CSC pool. ...
Elevated Nanog is associated with poorer outcome in numerous epithelial malignancies. Nanog is enriched in CSCs and ablation o …
PEST motif sequence regulating human NANOG for proteasomal degradation.
Ramakrishna S, Suresh B, Lim KH, Cha BH, Lee SH, Kim KS, Baek KH. Ramakrishna S, et al. Stem Cells Dev. 2011 Sep;20(9):1511-9. doi: 10.1089/scd.2010.0410. Epub 2011 Mar 12. Stem Cells Dev. 2011. PMID: 21299413
The expression level of NANOG is tightly regulated, and perturbation in its expression level can lead to significant difference in the morphology, expression of cell surface markers, and growth factor dependence of human and mouse ESCs. Here, we demonstrate that the …
The expression level of NANOG is tightly regulated, and perturbation in its expression level can lead to significant difference in th …
4,619 results