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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 4
1957 1
1964 4
1965 1
1969 2
1972 2
1973 1
1974 1
1975 4
1976 1
1977 1
1978 2
1979 1
1980 2
1981 2
1982 3
1983 4
1984 1
1985 3
1986 3
1987 3
1988 8
1989 3
1990 9
1991 5
1992 5
1993 2
1994 5
1995 6
1996 8
1997 6
1998 6
1999 5
2000 7
2001 8
2002 20
2003 17
2004 33
2005 18
2006 28
2007 31
2008 19
2009 26
2010 23
2011 37
2012 32
2013 25
2014 39
2015 41
2016 29
2017 37
2018 29
2019 27
2020 25
2021 22
2022 26
2023 17
2024 4

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Search Results

665 results

Results by year

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Page 1
RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Wang J, Miao Y, Wicklein R, Sun Z, Wang J, Jude KM, Fernandes RA, Merrill SA, Wernig M, Garcia KC, Südhof TC. Wang J, et al. Cell. 2021 Nov 24;184(24):5869-5885.e25. doi: 10.1016/j.cell.2021.10.016. Epub 2021 Nov 9. Cell. 2021. PMID: 34758294 Free PMC article.
RTN4-binding proteins were widely studied as "NoGo" receptors, but their physiological interactors and roles remain elusive. ...Thus, BAI binding to RTN4/NoGo receptors represents a receptor-ligand axis that, enabled by rare post-translational m …
RTN4-binding proteins were widely studied as "NoGo" receptors, but their physiological interactors and roles remain elusive. . …
Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2.
Rodriguez CM, Bechek SC, Jones GL, Nakayama L, Akiyama T, Kim G, Solow-Cordero DE, Strittmatter SM, Gitler AD. Rodriguez CM, et al. Cell Rep. 2022 Oct 25;41(4):111505. doi: 10.1016/j.celrep.2022.111505. Cell Rep. 2022. PMID: 36288715 Free PMC article.
Here, we perform a genome-wide arrayed small interfering RNA (siRNA) screen in human cells and identify RTN4R, the gene encoding the RTN4/NoGo-Receptor, as a potent modifier of ataxin-2 levels. ...These data define the RTN4/NoGo-Receptor as a no …
Here, we perform a genome-wide arrayed small interfering RNA (siRNA) screen in human cells and identify RTN4R, the gene encoding the …
Function of Nogo-A/Nogo-A receptor in Alzheimer's disease.
Xu YQ, Sun ZQ, Wang YT, Xiao F, Chen MW. Xu YQ, et al. CNS Neurosci Ther. 2015 Jun;21(6):479-85. doi: 10.1111/cns.12387. Epub 2015 Mar 2. CNS Neurosci Ther. 2015. PMID: 25732725 Free PMC article. Review.
Particularly, Nogo-A/Nogo-A receptors modulate the generation of amyloid beta-protein (Abeta), which is thought to be a major cause of AD. ...We concluded the Nogo-A/Nogo-A receptor provide new insight into potential mechanisms and promis …
Particularly, Nogo-A/Nogo-A receptors modulate the generation of amyloid beta-protein (Abeta), which is thought to be a …
Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma.
Hong JH, Kang S, Sa JK, Park G, Oh YT, Kim TH, Yin J, Kim SS, D'Angelo F, Koo H, You Y, Park S, Kwon HJ, Kim CI, Ryu H, Lin W, Park EJ, Kim YJ, Park MJ, Kim H, Kim MS, Chung S, Park CK, Park SH, Kang YH, Kim JH, Saya H, Nakano I, Gwak HS, Yoo H, Lee J, Hur EM, Shi B, Nam DH, Iavarone A, Lee SH, Park JB. Hong JH, et al. Brain. 2021 Mar 3;144(2):636-654. doi: 10.1093/brain/awaa408. Brain. 2021. PMID: 33479772
Here, we adopted radiogenomic analysis to screen for functionally relevant genes that orchestrate the process of glioma cell infiltration through myelin and promote glioblastoma aggressiveness. The receptor of the Nogo ligand (NgR1) was selected as the top candidate …
Here, we adopted radiogenomic analysis to screen for functionally relevant genes that orchestrate the process of glioma cell infiltration th …
Nogo receptor decoy promotes recovery and corticospinal growth in non-human primate spinal cord injury.
Wang X, Zhou T, Maynard GD, Terse PS, Cafferty WB, Kocsis JD, Strittmatter SM. Wang X, et al. Brain. 2020 Jun 1;143(6):1697-1713. doi: 10.1093/brain/awaa116. Brain. 2020. PMID: 32375169 Free PMC article.
Among limitations on neural recovery are myelin-associated inhibitors functioning as ligands for neuronal Nogo receptor 1 (NgR1). A soluble decoy (NgR1-Fc, AXER-204) blocks these ligands and provides a means to promote recovery of function in multiple preclinical ro …
Among limitations on neural recovery are myelin-associated inhibitors functioning as ligands for neuronal Nogo receptor 1 (NgR …
Nogo and Nogo receptor: relevance to schizophrenia?
Willi R, Schwab ME. Willi R, et al. Neurobiol Dis. 2013 Jun;54:150-7. doi: 10.1016/j.nbd.2013.01.011. Epub 2013 Jan 28. Neurobiol Dis. 2013. PMID: 23369871 Review.
The membrane protein Nogo-A and its receptor NgR have been extensively characterized for their role in restricting axonal growth, regeneration, and plasticity in the central nervous system. Recent evidence suggests that Nogo and NgR might constitute candidate …
The membrane protein Nogo-A and its receptor NgR have been extensively characterized for their role in restricting axonal grow …
Soluble Nogo-Receptor-Fc decoy (AXER-204) in patients with chronic cervical spinal cord injury in the USA: a first-in-human and randomised clinical trial.
Maynard G, Kannan R, Liu J, Wang W, Lam TKT, Wang X, Adamson C, Hackett C, Schwab JM, Liu C, Leslie DP, Chen D, Marino R, Zafonte R, Flanders A, Block G, Smith E, Strittmatter SM. Maynard G, et al. Lancet Neurol. 2023 Aug;22(8):672-684. doi: 10.1016/S1474-4422(23)00215-6. Lancet Neurol. 2023. PMID: 37479373 Clinical Trial.
BACKGROUND: Spinal cord injury (SCI) causes neural disconnection and persistent neurological deficits, so axon sprouting and plasticity might promote recovery. Soluble Nogo-Receptor-Fc decoy (AXER-204) blocks inhibitors of axon growth and promotes recovery of motor …
BACKGROUND: Spinal cord injury (SCI) causes neural disconnection and persistent neurological deficits, so axon sprouting and plasticity migh …
Nogo and the Nogo-66 receptor.
Fournier AE, GrandPré T, Gould G, Wang X, Strittmatter SM. Fournier AE, et al. Prog Brain Res. 2002;137:361-9. doi: 10.1016/s0079-6123(02)37027-4. Prog Brain Res. 2002. PMID: 12440378 Review.
We have identified a brain-specific, leucine-rich repeat protein with high affinity for soluble Nogo-66. Cleavage of the Nogo-66 receptor from axonal surfaces renders neurons insensitive to Nogo-66. Nogo-66 receptor expression is sufficie …
We have identified a brain-specific, leucine-rich repeat protein with high affinity for soluble Nogo-66. Cleavage of the Nogo- …
Nogo-B receptor in relevant carcinoma: Current achievements, challenges and aims (Review).
Li YK, Xie YJ, Wu DC, Long SL, Tang S, Mo ZC. Li YK, et al. Int J Oncol. 2018 Nov;53(5):1827-1835. doi: 10.3892/ijo.2018.4520. Epub 2018 Aug 9. Int J Oncol. 2018. PMID: 30106141 Review.
The novel neurite outgrowth inhibitor B (Nogo-B) receptor (NgBR) is specific for Nogo-B, which is highly expressed in various human organs and cells, including the lung, liver, kidney, smooth muscle cells, blood vessel endothelial cells and inflammator …
The novel neurite outgrowth inhibitor B (Nogo-B) receptor (NgBR) is specific for Nogo-B, which is highly expressed in v …
NgR1 is an NK cell inhibitory receptor that destabilizes the immunological synapse.
Oh SC, Kim SE, Jang IH, Kim SM, Lee SY, Lee S, Chu IS, Yoon SR, Jung H, Choi I, Doh J, Kim TD. Oh SC, et al. Nat Immunol. 2023 Mar;24(3):463-473. doi: 10.1038/s41590-022-01394-w. Epub 2023 Jan 9. Nat Immunol. 2023. PMID: 36624164
Despite an advanced understanding of the characteristics of the IS and its formation processes, the mechanisms that regulate its stability via the cytoskeleton are unclear. Here, we show that Nogo receptor 1 (NgR1) has an important function in modulating NK cell-med …
Despite an advanced understanding of the characteristics of the IS and its formation processes, the mechanisms that regulate its stability v …
665 results