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Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer's disease.
Kenche VB, Hung LW, Perez K, Volitakes I, Ciccotosto G, Kwok J, Critch N, Sherratt N, Cortes M, Lal V, Masters CL, Murakami K, Cappai R, Adlard PA, Barnham KJ. Kenche VB, et al. Among authors: hung lw. Angew Chem Int Ed Engl. 2013 Mar 18;52(12):3374-8. doi: 10.1002/anie.201209885. Epub 2013 Feb 10. Angew Chem Int Ed Engl. 2013. PMID: 23401085 No abstract available.
Analysis of Abeta interactions using ProteinChip technology.
Giannakis E, Hung LW, Camacaro KP, Smith DP, Barnham KJ, Wade JD. Giannakis E, et al. Among authors: hung lw. Methods Mol Biol. 2008;494:71-86. doi: 10.1007/978-1-59745-419-3_5. Methods Mol Biol. 2008. PMID: 18726569
The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity.
Crouch PJ, Savva MS, Hung LW, Donnelly PS, Mot AI, Parker SJ, Greenough MA, Volitakis I, Adlard PA, Cherny RA, Masters CL, Bush AI, Barnham KJ, White AR. Crouch PJ, et al. Among authors: hung lw. J Neurochem. 2011 Oct;119(1):220-30. doi: 10.1111/j.1471-4159.2011.07402.x. Epub 2011 Aug 25. J Neurochem. 2011. PMID: 21797865 Free article.
Dimeric structures of alpha-synuclein bind preferentially to lipid membranes.
Giannakis E, Pacífico J, Smith DP, Hung LW, Masters CL, Cappai R, Wade JD, Barnham KJ. Giannakis E, et al. Among authors: hung lw. Biochim Biophys Acta. 2008 Apr;1778(4):1112-9. doi: 10.1016/j.bbamem.2008.01.012. Epub 2008 Jan 26. Biochim Biophys Acta. 2008. PMID: 18261456 Free article.
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Crouch PJ, Hung LW, Adlard PA, Cortes M, Lal V, Filiz G, Perez KA, Nurjono M, Caragounis A, Du T, Laughton K, Volitakis I, Bush AI, Li QX, Masters CL, Cappai R, Cherny RA, Donnelly PS, White AR, Barnham KJ. Crouch PJ, et al. Among authors: hung lw. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):381-6. doi: 10.1073/pnas.0809057106. Epub 2009 Jan 2. Proc Natl Acad Sci U S A. 2009. PMID: 19122148 Free PMC article.
112 results