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A Driver Never Works Alone-Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human Cancer.
Grzes M, Oron M, Staszczak Z, Jaiswar A, Nowak-Niezgoda M, Walerych D. Grzes M, et al. Cancers (Basel). 2020 Jun 11;12(6):1532. doi: 10.3390/cancers12061532. Cancers (Basel). 2020. PMID: 32545208 Free PMC article. Review.
Each of these universal oncogenic factors-mutant p53, KRAS and CMYC proteins, telomerase ribonucleoprotein, proteasome machinery, HSP molecular chaperones, NF-kappaB and WNT pathways, AP-1 and YAP/TAZ transcription factors and non-coding RNAs-has a vast network of molecular inter …
Each of these universal oncogenic factors-mutant p53, KRAS and CMYC proteins, telomerase ribonucleoprotein, proteasome machinery, HSP molecu …