Imidazopyridine-Based Thiazole Derivatives as Potential Antidiabetic Agents: Synthesis, In Vitro Bioactivity, and In Silico Molecular Modeling Approach.
Hussain R, Rehman W, Khan S, Maalik A, Hefnawy M, Alanazi AS, Khan Y, Rasheed L.
Hussain R, et al.
Pharmaceuticals (Basel). 2023 Sep 13;16(9):1288. doi: 10.3390/ph16091288.
Pharmaceuticals (Basel). 2023.
PMID: 37765096
Free PMC article.
The obtained results suggested that compounds 4a (docking score = -13.45), 4g (docking score = -12.87), 4o (docking score = -12.15), and 4p (docking score = -11.25) remarkably showed superior activity against the targeted alpha-glucosidase enzyme, with IC(50) values of 5.57 3.45, …
The obtained results suggested that compounds 4a (docking score = -13.45), 4g (docking score = -12.87), 4o (docking score = -12.15), and 4p …