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Copy number variation and selection during reprogramming to pluripotency.
Hussein SM, Batada NN, Vuoristo S, Ching RW, Autio R, Närvä E, Ng S, Sourour M, Hämäläinen R, Olsson C, Lundin K, Mikkola M, Trokovic R, Peitz M, Brüstle O, Bazett-Jones DP, Alitalo K, Lahesmaa R, Nagy A, Otonkoski T. Hussein SM, et al. Nature. 2011 Mar 3;471(7336):58-62. doi: 10.1038/nature09871. Nature. 2011. PMID: 21368824
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.
Rajala K, Lindroos B, Hussein SM, Lappalainen RS, Pekkanen-Mattila M, Inzunza J, Rozell B, Miettinen S, Narkilahti S, Kerkelä E, Aalto-Setälä K, Otonkoski T, Suuronen R, Hovatta O, Skottman H. Rajala K, et al. Among authors: hussein sm. PLoS One. 2010 Apr 19;5(4):e10246. doi: 10.1371/journal.pone.0010246. PLoS One. 2010. PMID: 20419109 Free PMC article.
An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator.
Lee DS, Shin JY, Tonge PD, Puri MC, Lee S, Park H, Lee WC, Hussein SM, Bleazard T, Yun JY, Kim J, Li M, Cloonan N, Wood D, Clancy JL, Mosbergen R, Yi JH, Yang KS, Kim H, Rhee H, Wells CA, Preiss T, Grimmond SM, Rogers IM, Nagy A, Seo JS. Lee DS, et al. Among authors: hussein sm. Nat Commun. 2014 Dec 10;5:5619. doi: 10.1038/ncomms6619. Nat Commun. 2014. PMID: 25493341 Free PMC article.
Small RNA changes en route to distinct cellular states of induced pluripotency.
Clancy JL, Patel HR, Hussein SM, Tonge PD, Cloonan N, Corso AJ, Li M, Lee DS, Shin JY, Wong JJ, Bailey CG, Benevento M, Munoz J, Chuah A, Wood D, Rasko JE, Heck AJ, Grimmond SM, Rogers IM, Seo JS, Wells CA, Puri MC, Nagy A, Preiss T. Clancy JL, et al. Among authors: hussein sm. Nat Commun. 2014 Dec 10;5:5522. doi: 10.1038/ncomms6522. Nat Commun. 2014. PMID: 25494340 Free article.
Divergent reprogramming routes lead to alternative stem-cell states.
Tonge PD, Corso AJ, Monetti C, Hussein SM, Puri MC, Michael IP, Li M, Lee DS, Mar JC, Cloonan N, Wood DL, Gauthier ME, Korn O, Clancy JL, Preiss T, Grimmond SM, Shin JY, Seo JS, Wells CA, Rogers IM, Nagy A. Tonge PD, et al. Among authors: hussein sm. Nature. 2014 Dec 11;516(7530):192-7. doi: 10.1038/nature14047. Nature. 2014. PMID: 25503232
85 results