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Potential peptides in atherosclerosis therapy.
Marleau S, Mellal K, Huynh DN, Ong H. Marleau S, et al. Front Horm Res. 2014;43:93-106. doi: 10.1159/000360568. Epub 2014 Jun 10. Front Horm Res. 2014. PMID: 24943301 Review.
Adiponectin has a pivotal role in the cardioprotective effect of CP-3(iv), a selective CD36 azapeptide ligand, after transient coronary artery occlusion in mice.
Huynh DN, Bessi VL, Ménard L, Piquereau J, Proulx C, Febbraio M, Lubell WD, Carpentier AC, Burelle Y, Ong H, Marleau S. Huynh DN, et al. FASEB J. 2018 Feb;32(2):807-818. doi: 10.1096/fj.201700505R. Epub 2018 Jan 4. FASEB J. 2018. PMID: 29018142
Hence, both paracrine and endocrine effects of adiponectin may contribute to reduced reactive oxygen species generation and apoptosis after MI/R, in a CD36-dependent manner.-Huynh, D. N., Bessi, V. L., Menard, L., Piquereau, J., Proulx, C., Febbraio, M., Lubell, W. …
Hence, both paracrine and endocrine effects of adiponectin may contribute to reduced reactive oxygen species generation and apoptosis after …
A cyclic azapeptide ligand of the scavenger receptor CD36/SR-B2 reduces the atherosclerotic lesion progression and enhances plaque stability in apolipoprotein E-deficient mice.
Gauvin J, Frégeau G, Elimam H, Ménard L, Huynh D, Lê C, Ahsanullah A, Lubell WD, Ong H, Marleau S. Gauvin J, et al. Among authors: huynh d. Front Pharmacol. 2023 May 30;14:1204905. doi: 10.3389/fphar.2023.1204905. eCollection 2023. Front Pharmacol. 2023. PMID: 37332345 Free PMC article.
431 results