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Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeleton.
Rahman P, Huysmans RD, Wiradjaja F, Gurung R, Ooms LM, Sheffield DA, Dyson JM, Layton MJ, Sriratana A, Takada H, Tiganis T, Mitchell CA. Rahman P, et al. Among authors: huysmans rd. J Biol Chem. 2011 Aug 26;286(34):29758-70. doi: 10.1074/jbc.M111.263103. Epub 2011 Jun 28. J Biol Chem. 2011. PMID: 21712384 Free PMC article.
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.
Gurung R, Tan A, Ooms LM, McGrath MJ, Huysmans RD, Munday AD, Prescott M, Whisstock JC, Mitchell CA. Gurung R, et al. Among authors: huysmans rd. J Biol Chem. 2003 Mar 28;278(13):11376-85. doi: 10.1074/jbc.M209991200. Epub 2003 Jan 20. J Biol Chem. 2003. PMID: 12536145 Free article.