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[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P. Pascoal TA, et al. Among authors: hyman bt. Nat Commun. 2022 Jul 19;13(1):4171. doi: 10.1038/s41467-022-30653-5. Nat Commun. 2022. PMID: 35853847 Free PMC article.
Amyloid, dementia and Alzheimer's disease.
Hyman BT, Tanzi RE. Hyman BT, et al. Curr Opin Neurol Neurosurg. 1992 Feb;5(1):88-93. Curr Opin Neurol Neurosurg. 1992. PMID: 1623244 Review.
Alzheimer disease therapeutics.
Irizarry MC, Hyman BT. Irizarry MC, et al. Among authors: hyman bt. J Neuropathol Exp Neurol. 2001 Oct;60(10):923-8. doi: 10.1093/jnen/60.10.923. J Neuropathol Exp Neurol. 2001. PMID: 11589422 Review.
The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.
Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL. Dickerson BC, et al. Among authors: hyman bt. Cereb Cortex. 2009 Mar;19(3):497-510. doi: 10.1093/cercor/bhn113. Epub 2008 Jul 16. Cereb Cortex. 2009. PMID: 18632739 Free PMC article.
Caspase activation precedes and leads to tangles.
de Calignon A, Fox LM, Pitstick R, Carlson GA, Bacskai BJ, Spires-Jones TL, Hyman BT. de Calignon A, et al. Among authors: hyman bt. Nature. 2010 Apr 22;464(7292):1201-4. doi: 10.1038/nature08890. Epub 2010 Mar 31. Nature. 2010. PMID: 20357768 Free PMC article.
833 results