Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 1
2003 1
2004 4
2007 2
2008 3
2010 3
2011 4
2012 2
2013 4
2014 7
2015 5
2016 4
2017 6
2018 4
2019 6
2020 9
2021 15
2022 9
2023 16
2024 8

Text availability

Article attribute

Article type

Publication date

Search Results

105 results

Results by year

Filters applied: . Clear all
Page 1
Immunological differences between primary and metastatic breast cancer.
Szekely B, Bossuyt V, Li X, Wali VB, Patwardhan GA, Frederick C, Silber A, Park T, Harigopal M, Pelekanou V, Zhang M, Yan Q, Rimm DL, Bianchini G, Hatzis C, Pusztai L. Szekely B, et al. Ann Oncol. 2018 Nov 1;29(11):2232-2239. doi: 10.1093/annonc/mdy399. Ann Oncol. 2018. PMID: 30203045 Free article.
BACKGROUND: Little is known about how the immune microenvironment of breast cancer evolves during disease progression. PATIENTS AND METHODS: We compared tumor infiltrating lymphocyte (TIL) count, programmed death-ligand 1 (PD-L1) protein expression by immunohistochemistry …
BACKGROUND: Little is known about how the immune microenvironment of breast cancer evolves during disease progression. PATIENTS AND M …
PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p.
Zhang Y, Chen C, Liu Z, Guo H, Lu W, Hu W, Lin Z. Zhang Y, et al. J Exp Clin Cancer Res. 2022 Mar 28;41(1):111. doi: 10.1186/s13046-022-02339-9. J Exp Clin Cancer Res. 2022. PMID: 35346324 Free PMC article.
Functionally, PABPC1 overexpression enhanced esophageal squamous cell proliferation and invasion by activating the IFN/IFI27 signaling pathway. PABPC1 interacted with eIF4G to increase the stability of IFI27 mRNA by competing with RNA exosomes in ESCC. ...CONCLUSION …
Functionally, PABPC1 overexpression enhanced esophageal squamous cell proliferation and invasion by activating the IFN/IFI27 signalin …
Emerging roles of FAM14 family members (G1P3/ISG 6-16 and ISG12/IFI27) in innate immunity and cancer.
Cheriyath V, Leaman DW, Borden EC. Cheriyath V, et al. J Interferon Cytokine Res. 2011 Jan;31(1):173-81. doi: 10.1089/jir.2010.0105. Epub 2010 Oct 12. J Interferon Cytokine Res. 2011. PMID: 20939681 Free PMC article. Review.
Here, we review the regulation and cellular functions of 2 related ISGs, ISG12 (IFI27) and G1P3 (ISG 6-16), that are commonly induced by IFNs in most, if not all, IFN-responsive cells. ...
Here, we review the regulation and cellular functions of 2 related ISGs, ISG12 (IFI27) and G1P3 (ISG 6-16), that are commonly induced …
ATM Inhibition-Induced ISG15/IFI27/OASL Is Correlated with Immunotherapy Response and Inflamed Immunophenotype.
Huang CH, Huang YC, Xu JK, Chen SY, Tseng LC, Huang JL, Lin CS. Huang CH, et al. Cells. 2023 Apr 30;12(9):1288. doi: 10.3390/cells12091288. Cells. 2023. PMID: 37174688 Free PMC article.
In oral cancer, high expressions of ISG15, IFI27, and OASL were associated with low expressions of ATM, the activation of inflamed immune pathways, and increased tumor-infiltrating scores of CD8+ T, natural killer, and dendritic cells. The high expressions of ISG15, …
In oral cancer, high expressions of ISG15, IFI27, and OASL were associated with low expressions of ATM, the activation of infl …
Interferon alpha-inducible protein 27 (IFI27) is a prognostic marker for pancreatic cancer based on comprehensive bioinformatics analysis.
Huang S, Zhao J, Song J, Li Y, Zuo R, Sa Y, Ma Z, OuYang H. Huang S, et al. Bioengineered. 2021 Dec;12(1):8515-8528. doi: 10.1080/21655979.2021.1985858. Bioengineered. 2021. PMID: 34592906 Free PMC article.
Here, we combined multiple datasets (GEO, TCGA and GTEx) to conduct a comprehensive analysis of pancreatic cancer. Through an in-depth analysis, we discovered that the expression of the gene encoding interferon alpha-inducible protein 27 (IFI27) was significantly hi …
Here, we combined multiple datasets (GEO, TCGA and GTEx) to conduct a comprehensive analysis of pancreatic cancer. Through an in-dept …
IFI27/ISG12 Downregulates Estrogen Receptor alpha Transactivation by Facilitating Its Interaction With CRM1/XPO1 in Breast Cancer Cells.
Cervantes-Badillo MG, Paredes-Villa A, Gómez-Romero V, Cervantes-Roldán R, Arias-Romero LE, Villamar-Cruz O, González-Montiel M, Barrios-García T, Cabrera-Quintero AJ, Rodríguez-Gómez G, Cancino-Villeda L, Zentella-Dehesa A, León-Del-Río A. Cervantes-Badillo MG, et al. Front Endocrinol (Lausanne). 2020 Oct 7;11:568375. doi: 10.3389/fendo.2020.568375. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33117284 Free PMC article.
IFI27/ISG12 overexpression was shown to impair the estradiol-dependent proliferation and tamoxifen-induced apoptosis in breast cancer cells. ...We propose that IFI27/ISG12 may be a potential target of future strategies to control the growth and proliferation
IFI27/ISG12 overexpression was shown to impair the estradiol-dependent proliferation and tamoxifen-induced apoptosis in breast can
Knockdown of IFI27 inhibits cell proliferation and invasion in oral squamous cell carcinoma.
Wang H, Qiu X, Lin S, Chen X, Wang T, Liao T. Wang H, et al. World J Surg Oncol. 2018 Mar 27;16(1):64. doi: 10.1186/s12957-018-1371-0. World J Surg Oncol. 2018. PMID: 29580248 Free PMC article.
MTT assay was used to detect the effect of -IFI27 knockdown on cell proliferation; Annexin V-PI staining flow cytometry was used to detect the effect of IFI27 downregulation on apoptosis of cancer cells. The effect of IFI27 downregulation on oral ca
MTT assay was used to detect the effect of -IFI27 knockdown on cell proliferation; Annexin V-PI staining flow cytometry was used to d …
Single-cell sequencing provides insights into the landscape of ovary in PCOS and alterations induced by CUMS.
Zuo W, Liu X, Chen J, Zuo W, Yin Y, Nie X, Tang P, Huang Y, Yu Q, Hu Q, Zhou J, Tan Y, Huang X, Ren Q. Zuo W, et al. Am J Physiol Endocrinol Metab. 2023 Oct 1;325(4):E346-E362. doi: 10.1152/ajpendo.00165.2023. Epub 2023 Aug 16. Am J Physiol Endocrinol Metab. 2023. PMID: 37584608
In theca cells (TCs), nine clusters were observed and some of them were relevant to inflammation, ER stress, and lipid metabolism. DEGs Ass1, Insl3, and Ifi27 were positively related to Cyp17a1, and Ces1d might contribute to the different trajectory of TCs. ...
In theca cells (TCs), nine clusters were observed and some of them were relevant to inflammation, ER stress, and lipid metabolism. DEGs Ass1 …
IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study.
Shojaei M, Shamshirian A, Monkman J, Grice L, Tran M, Tan CW, Teo SM, Rodrigues Rossi G, McCulloch TR, Nalos M, Raei M, Razavi A, Ghasemian R, Gheibi M, Roozbeh F, Sly PD, Spann KM, Chew KY, Zhu Y, Xia Y, Wells TJ, Senegaglia AC, Kuniyoshi CL, Franck CL, Dos Santos AFR, de Noronha L, Motamen S, Valadan R, Amjadi O, Gogna R, Madan E, Alizadeh-Navaei R, Lamperti L, Zuñiga F, Nova-Lamperti E, Labarca G, Knippenberg B, Herwanto V, Wang Y, Phu A, Chew T, Kwan T, Kim K, Teoh S, Pelaia TM, Kuan WS, Jee Y, Iredell J, O'Byrne K, Fraser JF, Davis MJ, Belz GT, Warkiani ME, Gallo CS, Souza-Fonseca-Guimaraes F, Nguyen Q, Mclean A, Kulasinghe A, Short KR, Tang B. Shojaei M, et al. Front Immunol. 2023 Jan 5;13:1060438. doi: 10.3389/fimmu.2022.1060438. eCollection 2022. Front Immunol. 2023. PMID: 36685600 Free PMC article.
METHODS: We conducted a multi-cohort observational study to investigate the biology and the prognostic role of interferon alpha-inducible protein 27 (IFI27) in COVID-19 patients. RESULTS: We show that IFI27 is expressed in the respiratory tract of COVID-19 patients …
METHODS: We conducted a multi-cohort observational study to investigate the biology and the prognostic role of interferon alpha-inducible pr …
Epstein-Barr virus lytic gene BNRF1 promotes B-cell lymphomagenesis via IFI27 upregulation.
Sagou K, Sato Y, Okuno Y, Watanabe T, Inagaki T, Motooka Y, Toyokuni S, Murata T, Kiyoi H, Kimura H. Sagou K, et al. PLoS Pathog. 2024 Feb 1;20(2):e1011954. doi: 10.1371/journal.ppat.1011954. eCollection 2024 Feb. PLoS Pathog. 2024. PMID: 38300891 Free PMC article.
RNA-seq analyses revealed that BNRF1 elicited the expression of interferon-inducible protein 27 (IFI27), which promotes cell proliferation. IFI27 knockdown in LCLs-WT resulted in excessive production of reactive oxygen species, leading to cell death and significantl …
RNA-seq analyses revealed that BNRF1 elicited the expression of interferon-inducible protein 27 (IFI27), which promotes cell prolifer …
105 results