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Pan-cancer analyses reveal IGSF10 as an immunological and prognostic biomarker.
Zhou Y, Gao M, Jing Y, Wang X. Zhou Y, et al. Front Genet. 2023 Jan 4;13:1032382. doi: 10.3389/fgene.2022.1032382. eCollection 2022. Front Genet. 2023. PMID: 36685968 Free PMC article.
However, the function of IGSF10 in pan-cancer stays unclear. We aimed to analyze the immunological and prognostic value of IGSF10 in pan-cancer. ...Results: We noticed low expression of IGSF10 in most cancer types. IGSF10 expressio …
However, the function of IGSF10 in pan-cancer stays unclear. We aimed to analyze the immunological and prognostic value of …
Identification of prognostic markers of lung cancer through bioinformatics analysis and in vitro experiments.
Ling B, Liao X, Huang Y, Liang L, Jiang Y, Pang Y, Qi G. Ling B, et al. Int J Oncol. 2020 Jan;56(1):193-205. doi: 10.3892/ijo.2019.4926. Epub 2019 Nov 28. Int J Oncol. 2020. PMID: 31789390 Free PMC article.
In patients with lung cancer, IGSF10 expression was decreased, and the overall survival time of patients with lung cancer was significantly shortened. ...Therefore, IGSF10 my serve as a potential prognostic marker of lung cancer....
In patients with lung cancer, IGSF10 expression was decreased, and the overall survival time of patients with lung cancer …
Immunoglobulin superfamily member 10 is a novel prognostic biomarker for breast cancer.
Wang M, Dai M, Wu YS, Yi Z, Li Y, Ren G. Wang M, et al. PeerJ. 2020 Oct 21;8:e10128. doi: 10.7717/peerj.10128. eCollection 2020. PeerJ. 2020. PMID: 33150070 Free PMC article.
Currently, the role and possible mechanism of IGSF10 in breast cancer remain unclear. METHOD: By applying real-time quantitative polymerase chain reaction (qRT-PCR) and immunohistochemistry (IHC), the expression of IGSF10 in breast cancer cells and tis …
Currently, the role and possible mechanism of IGSF10 in breast cancer remain unclear. METHOD: By applying real-time quantitati …
MicroRNA-106b-5p inhibits growth and progression of lung adenocarcinoma cells by downregulating IGSF10.
Ling B, Liao X, Tang Q, Ye G, Bin X, Wang J, Pang Y, Qi G. Ling B, et al. Aging (Albany NY). 2021 Jul 29;13(14):18740-18756. doi: 10.18632/aging.203318. Epub 2021 Jul 29. Aging (Albany NY). 2021. PMID: 34351868 Free PMC article.
In this study, we investigated the mechanistic role and prognostic significance of IGSF10 in lung adenocarcinoma. Oncomine database analysis showed that IGSF10 expression was significantly reduced in most cancer types, including lung adenocarcinoma (LUAD). .. …
In this study, we investigated the mechanistic role and prognostic significance of IGSF10 in lung adenocarcinoma. Oncomine database a …
Identification of Novel Biomarkers Associated With the Prognosis and Potential Pathogenesis of Breast Cancer via Integrated Bioinformatics Analysis.
Wu M, Li Q, Wang H. Wu M, et al. Technol Cancer Res Treat. 2021 Jan-Dec;20:1533033821992081. doi: 10.1177/1533033821992081. Technol Cancer Res Treat. 2021. PMID: 33550915 Free PMC article.
Two novel biomarkers, ADH1A and IGSF10, and 4 other genes (APOD, KIT, RBP4, and SFRP1) that were implicated in the prognosis and pathogenesis of breast cancer, exhibited low expression levels in breast cancer tissues. ...CONCLUSION: ADH1A, IGSF10, and …
Two novel biomarkers, ADH1A and IGSF10, and 4 other genes (APOD, KIT, RBP4, and SFRP1) that were implicated in the prognosis and path …
Identification of Metastasis-Associated Genes in Triple-Negative Breast Cancer Using Weighted Gene Co-expression Network Analysis.
Xie W, Du Z, Chen Y, Liu N, Zhong Z, Shen Y, Tang L. Xie W, et al. Evol Bioinform Online. 2020 Sep 1;16:1176934320954868. doi: 10.1177/1176934320954868. eCollection 2020. Evol Bioinform Online. 2020. PMID: 32952395 Free PMC article.
Triple-negative breast cancer (TNBC) is the most aggressive and fatal sub-type of breast cancer. ...In this module, 64 genes were identified, and its functional enrichment analysis revealed that they were mainly associated with transcriptional misregulation in ca …
Triple-negative breast cancer (TNBC) is the most aggressive and fatal sub-type of breast cancer. ...In this module, 64 genes w …
IGSF10 inhibits the metastasis of lung adenocarcinoma via the Spi-B/Integrin-beta1 signaling pathway.
Ling B, Ye G, Qin C, Liao X, Yang R, Su L, Qi G. Ling B, et al. J Biochem Mol Toxicol. 2024 Apr;38(4):e23693. doi: 10.1002/jbt.23693. J Biochem Mol Toxicol. 2024. PMID: 38622980
Importantly, IGSF10 regulates the metastatic ability of LUAD cells in vitro and in vivo. ...These findings gave credence to the premise that IGSF10 performed a crucial function in LUAD....
Importantly, IGSF10 regulates the metastatic ability of LUAD cells in vitro and in vivo. ...These findings gave credence to the premi …
Unravelling of the comparative Transcriptomic Profile of Gallbladder Cancer using mRNA sequencing.
Dixit R, Pandey M, Rajput M, Shukla VK. Dixit R, et al. Mol Biol Rep. 2022 Jul;49(7):6395-6403. doi: 10.1007/s11033-022-07448-4. Epub 2022 Apr 25. Mol Biol Rep. 2022. PMID: 35469389
BACKGROUND: Gallbladder cancer (GBC) represents a wide geographical diversity as well as heterogeneity in clinical and genomic landscape. ...RESULTS: A total of 954 differentially expressed mRNA transcripts were identified, including overexpression of REG4, TMEM238, S100A2 …
BACKGROUND: Gallbladder cancer (GBC) represents a wide geographical diversity as well as heterogeneity in clinical and genomic landsc …
Identification of novel mutations in endometrial cancer patients by whole-exome sequencing.
Chang YS, Huang HD, Yeh KT, Chang JG. Chang YS, et al. Int J Oncol. 2017 May;50(5):1778-1784. doi: 10.3892/ijo.2017.3919. Epub 2017 Mar 20. Int J Oncol. 2017. PMID: 28339086
The aim of the present study was to identify genomic alterations in Taiwanese endometrial cancer patients. This information is vitally important in Taiwan, where endometrial cancer is the second most common gynecological cancer. ...We identified 143 non-synon …
The aim of the present study was to identify genomic alterations in Taiwanese endometrial cancer patients. This information is vitall …
Exome sequencing in one family with gastric- and rectal cancer.
Thutkawkorapin J, Picelli S, Kontham V, Liu T, Nilsson D, Lindblom A. Thutkawkorapin J, et al. BMC Genet. 2016 Feb 13;17:41. doi: 10.1186/s12863-016-0351-z. BMC Genet. 2016. PMID: 26872740 Free PMC article.
BACKGROUND: Heritable factors are well known to increase the risk of cancer in families. Known susceptibility genes account for a small proportion of all colorectal cancer cases. The aim of this study was to identify the genetic background in a family suggested to s …
BACKGROUND: Heritable factors are well known to increase the risk of cancer in families. Known susceptibility genes account for a sma …
14 results