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Year Number of Results
1971 1
1983 1
1987 5
1988 62
1989 287
1990 507
1991 804
1992 1130
1993 1306
1994 1618
1995 1704
1996 1763
1997 1796
1998 1939
1999 1909
2000 2139
2001 2057
2002 2215
2003 2369
2004 2650
2005 3141
2006 3379
2007 3665
2008 4301
2009 4685
2010 5292
2011 5955
2012 6574
2013 7140
2014 7816
2015 8392
2016 8634
2017 9435
2018 10017
2019 10794
2020 13060
2021 14488
2022 14582
2023 13192
2024 4877

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165,044 results

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Page 1
Defining IL-6 levels in healthy individuals: A meta-analysis.
Said EA, Al-Reesi I, Al-Shizawi N, Jaju S, Al-Balushi MS, Koh CY, Al-Jabri AA, Jeyaseelan L. Said EA, et al. J Med Virol. 2021 Jun;93(6):3915-3924. doi: 10.1002/jmv.26654. Epub 2020 Nov 22. J Med Virol. 2021. PMID: 33155686 Review.
In vivo immunomodulation of IL6 signaling in a murine multiple trauma model.
Malysch T, Reinhold JM, Becker CA, Schmidt-Bleek K, Kleber C. Malysch T, et al. Immunol Res. 2023 Apr;71(2):164-172. doi: 10.1007/s12026-022-09319-3. Epub 2022 Sep 24. Immunol Res. 2023. PMID: 36151360 Free PMC article.
A significant number of trauma patients die during the ICU phase of care because of a severe immune response. Interleukin-6 (IL6) plays a central role within that immune response, signaling through a membrane-bound (IL6-R) and a soluble IL6 receptor (sIL6-R). …
A significant number of trauma patients die during the ICU phase of care because of a severe immune response. Interleukin-6 (IL6) pla …
IL-6 and NF-IL6 in acute-phase response and viral infection.
Akira S, Kishimoto T. Akira S, et al. Immunol Rev. 1992 Jun;127:25-50. doi: 10.1111/j.1600-065x.1992.tb01407.x. Immunol Rev. 1992. PMID: 1380488 Review.
NF-IL6 was originally identified as a DNA-binding protein responsible for IL-1-stimulated IL-6 induction. ...Furthermore, NF-IL6 is shown to be identical to IL-6DBP, a DNA-binding protein responsible for IL-6-mediated induction in acute-phase proteins, demonstrating …
NF-IL6 was originally identified as a DNA-binding protein responsible for IL-1-stimulated IL-6 induction. ...Furthermore, NF-IL6 …
[Investigation of IL6 expression in patients with colorectal adenocarcinoma].
Jósa V, Féderer K, Zrubka Z, Reiniger L, Baranyai Z. Jósa V, et al. Orv Hetil. 2021 Sep 12;162(37):1502-1507. doi: 10.1556/650.2021.32206. Orv Hetil. 2021. PMID: 34516395 Hungarian.
However, the IL6 expression of the tumor cells did not correlate with sex, age, or tumor grade. DISCUSSION: There were differences between the IL6 expression in tumor cells and stromal cells. CONCLUSION: IL6 may be a useful marker and potential therapeutic ta …
However, the IL6 expression of the tumor cells did not correlate with sex, age, or tumor grade. DISCUSSION: There were differences be …
Expression profiles and function of IL6 in polymorphonuclear myeloid-derived suppressor cells.
Ibrahim ML, Lu C, Klement JD, Redd PS, Yang D, Smith AD, Liu K. Ibrahim ML, et al. Cancer Immunol Immunother. 2020 Nov;69(11):2233-2245. doi: 10.1007/s00262-020-02620-w. Epub 2020 Jun 1. Cancer Immunol Immunother. 2020. PMID: 32488308 Free PMC article.
Conversely, IL6-sufficient colon and pancreatic tumor grow at similar rate in WT and IL6-deficient mice. ...Our findings determine that a high tumor local IL6 threshold is essential for IL6 function in colon tumor promotion and targeting the IL6 …
Conversely, IL6-sufficient colon and pancreatic tumor grow at similar rate in WT and IL6-deficient mice. ...Our findings deter …
Regulation of expression of the interleukin 6 gene: structure and function of the transcription factor NF-IL6.
Akira S, Isshiki H, Nakajima T, Kinoshita S, Nishio Y, Natsuka S, Kishimoto T. Akira S, et al. Ciba Found Symp. 1992;167:47-62; discussion 62-7. doi: 10.1002/9780470514269.ch4. Ciba Found Symp. 1992. PMID: 1385054 Review.
C/EBP and NF-IL6 recognize the same nucleotide sequence, but exhibit distinct patterns of expression. ...Evidence that NF-IL6 DNA-binding activity is increased after IL-6 stimulation without increased NF-IL6 protein synthesis demonstrates the importance of po …
C/EBP and NF-IL6 recognize the same nucleotide sequence, but exhibit distinct patterns of expression. ...Evidence that NF-IL6 …
Beta-Lapachone Attenuates BMSC-Mediated Neuroblastoma Malignant Transformation by Inhibiting Gal-3/Gal-3BP/IL6 Axis.
Zhou Y, Yan H, Zhou Q, Feng R, Wang P, Yang F, Zhang Y, Yuan Z, Zhai B. Zhou Y, et al. Front Pharmacol. 2021 Nov 1;12:766909. doi: 10.3389/fphar.2021.766909. eCollection 2021. Front Pharmacol. 2021. PMID: 34790130 Free PMC article.
IL6 secretion from immortalized BMSC (iBMSC) was directly regulated by NB cells and is involved in promoting the proliferation and metastasis of NB cells. ...Our results reveal the effect of iBMSC-derived IL6 on TME-induced malignant transformation of NB cells, and …
IL6 secretion from immortalized BMSC (iBMSC) was directly regulated by NB cells and is involved in promoting the proliferation and me …
165,044 results
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