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Downregulation of CRX, a Group 3-specific oncogenic transcription factor, inhibits TGF-β/activin signaling in medulloblastoma cells.
Masurkar SA, Deogharkar A, Bharambe HS, Shirsat NV. Masurkar SA, et al. Biochem Biophys Res Commun. 2021 Sep 3;568:76-82. doi: 10.1016/j.bbrc.2021.06.064. Epub 2021 Jun 27. Biochem Biophys Res Commun. 2021. PMID: 34192607
CRX knockdown resulted in the downregulation of expression of several retina-specific genes like IMPG2, PDC, RCVRN. and Group 3 specific genes like GABRA5, MYC, PROM1. ...
CRX knockdown resulted in the downregulation of expression of several retina-specific genes like IMPG2, PDC, RCVRN. and Group 3 speci …
Proteomic profiling of medulloblastoma reveals novel proteins differentially expressed within each molecular subgroup.
Narayan V, Jaiswal J, Sugur H, Sd S, Rao S, Chatterjee A, Gowda H, A A, Somanna S, Santosh V. Narayan V, et al. Clin Neurol Neurosurg. 2020 Sep;196:106028. doi: 10.1016/j.clineuro.2020.106028. Epub 2020 Jun 17. Clin Neurol Neurosurg. 2020. PMID: 32580068
The top upregulated proteins were PMEL and FBN2 in the WNT subgroup, SYNGR2 in the SHH subgroup and GFAP, IMPG2 and MAGEA10 in the Non WNT/Non SHH group. We validated GFAP by immunohistochemistry on the archived samples (n = 118) and noted two types of staining pattern in …
The top upregulated proteins were PMEL and FBN2 in the WNT subgroup, SYNGR2 in the SHH subgroup and GFAP, IMPG2 and MAGEA10 in the No …
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples.
Northcott PA, Shih DJ, Remke M, Cho YJ, Kool M, Hawkins C, Eberhart CG, Dubuc A, Guettouche T, Cardentey Y, Bouffet E, Pomeroy SL, Marra M, Malkin D, Rutka JT, Korshunov A, Pfister S, Taylor MD. Northcott PA, et al. Acta Neuropathol. 2012 Apr;123(4):615-26. doi: 10.1007/s00401-011-0899-7. Epub 2011 Nov 6. Acta Neuropathol. 2012. PMID: 22057785 Free PMC article.
Serum Autoantibody Profiling of Patients with Paraneoplastic and Non-Paraneoplastic Autoimmune Retinopathy.
Ten Berge JC, van Rosmalen J, Vermeer J, Hellström C, Lindskog C, Nilsson P, Qundos U, Rothova A, Schreurs MW. Ten Berge JC, et al. PLoS One. 2016 Dec 8;11(12):e0167909. doi: 10.1371/journal.pone.0167909. eCollection 2016. PLoS One. 2016. PMID: 27930731 Free PMC article.
Logistic regressions were used to estimate the associations between ocular antigens and diagnosis. Validation of interphotoreceptor matrix proteoglycan 2 (IMPG2) and recoverin antigens was performed by immunohistochemistry and immunoblot, respectively. ...Validation of bea …
Logistic regressions were used to estimate the associations between ocular antigens and diagnosis. Validation of interphotoreceptor matrix p …