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Distinct patient responses to activation of T-cells by free HER-2, G89 (777-789) and protected LRMK-linked HER-2, {AE-39 [p776 (Ava-774-788)], AE-47 [(Ava-776-788)] and AE-37[p776 (774-788)]} peptides could lead to development of personalized cancer vaccines.
Li Y, Matsueda S, Efferson CL, Tsuda N, Kawano K, Gao H, Peoples GE, Ioannides CG. Li Y, et al. Anticancer Res. 2009 Jan;29(1):41-58. Anticancer Res. 2009. PMID: 19331132 Free article.
Preferential activation of Th1 cells in distinct individuals by AE-37, G89 and AE-39 indicates that cancer vaccines will benefit from correct individual and disease-associated help. Emergence of distinct daughters of luminal and myoepithelial BRC stem cells during metastas …
Preferential activation of Th1 cells in distinct individuals by AE-37, G89 and AE-39 indicates that cancer vaccines will benefit from …
A V141L polymorphism of the human LRMP gene is associated with survival of lung cancer patients.
Manenti G, Galbiati F, Pettinicchio A, Spinola M, Piconese S, Leoni VP, Conti B, Ravagnani F, Incarbone M, Pastorino U, Dragani TA. Manenti G, et al. Carcinogenesis. 2006 Jul;27(7):1386-90. doi: 10.1093/carcin/bgi332. Epub 2006 Jan 12. Carcinogenesis. 2006. PMID: 16410263
These findings suggest that the LRMP V141L polymorphism can predict survival in lung ADCA and that the role of LRMP and CASC1 in human lung cancer risk may differ from that in mice....
These findings suggest that the LRMP V141L polymorphism can predict survival in lung ADCA and that the role of LRMP and CASC1 in human lung …
Pulmonary adenoma susceptibility 1 (Pas1) locus affects inflammatory response.
Maria DA, Manenti G, Galbiati F, Ribeiro OG, Cabrera WH, Barrera RG, Pettinicchio A, De Franco M, Starobinas N, Siqueira M, Dragani TA, Ibañez OM. Maria DA, et al. Oncogene. 2003 Jan 23;22(3):426-32. doi: 10.1038/sj.onc.1206157. Oncogene. 2003. PMID: 12545163
These results provide a model to explore the mechanism underlying inherited predisposition to lung cancer in the context of a link to inflammation....
These results provide a model to explore the mechanism underlying inherited predisposition to lung cancer in the context of a link to …
Jaw1/LRMP, a germinal centre-associated marker for the immunohistological study of B-cell lymphomas.
Tedoldi S, Paterson JC, Cordell J, Tan SY, Jones M, Manek S, Dei Tos AP, Roberton H, Masir N, Natkunam Y, Pileri SA, Facchetti F, Hansmann ML, Mason DY, Marafioti T. Tedoldi S, et al. J Pathol. 2006 Aug;209(4):454-63. doi: 10.1002/path.2002. J Pathol. 2006. PMID: 16739114
It was absent, or present at only low levels, in mature T-cells, although cortical thymocytes were weakly positive. Among lymphoid neoplasms, Jaw1/LRMP was found in germinal centre-derived lymphomas (follicle centre lymphoma, Burkitt's lymphoma, lymphocyte-predominant Hodg …
It was absent, or present at only low levels, in mature T-cells, although cortical thymocytes were weakly positive. Among lymphoid neopla …