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Did you mean itgam cancer (254 results)?
ITGAV targeting as a therapeutic approach for treatment of metastatic breast cancer.
Cheuk IW, Siu MT, Ho JC, Chen J, Shin VY, Kwong A. Cheuk IW, et al. Am J Cancer Res. 2020 Jan 1;10(1):211-223. eCollection 2020. Am J Cancer Res. 2020. PMID: 32064162 Free PMC article.
The effectiveness of an ITGAV antagonist, cilengitide, for breast cancer treatment was investigated in vivo. ...Targeting ITGAV is a potential treatment for metastatic breast cancer as well as primary breast tumors with high ITGAV expression. .. …
The effectiveness of an ITGAV antagonist, cilengitide, for breast cancer treatment was investigated in vivo. ...Targeting I …
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis.
Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. Zhu Z, et al. Cell Stem Cell. 2020 Feb 6;26(2):187-204.e10. doi: 10.1016/j.stem.2019.11.016. Epub 2020 Jan 16. Cell Stem Cell. 2020. PMID: 31956038 Free PMC article.
As mechanisms of SOX2-mediated ZIKV infection, we identified inverse expression of antiviral interferon response genes (ISGs) and positive correlation with integrin alpha(v) (ITGAV). ZIKV infection was disrupted by genetic targeting of ITGAV or its binding partner I …
As mechanisms of SOX2-mediated ZIKV infection, we identified inverse expression of antiviral interferon response genes (ISGs) and positive c …
MiR-197 Inhibitor Loaded AbCD133@MSNs@GNR Affects the Development of Prostate Cancer Through Targeting ITGAV.
Ju G, Zhu Y, Du T, Cao W, Lin J, Li C, Xu D, Wang Z. Ju G, et al. Front Cell Dev Biol. 2021 Jun 14;9:646884. doi: 10.3389/fcell.2021.646884. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34195187 Free PMC article.
In this study, we verified that miR-197 is significantly overexpressed in prostate cancer tissues and prostate cancer cells. Then, we verified that miR-197 expression affects the proliferation, invasion, and metastasis of prostate cancer cells by regulating i …
In this study, we verified that miR-197 is significantly overexpressed in prostate cancer tissues and prostate cancer cells. T …
CASZ1 promotes migration, invasion, and metastasis of lung cancer cells by controlling expression of ITGAV.
Taheri Baghmisheh S, Wu YY, Wu JE, Hsu KF, Chen YL, Hong TM. Taheri Baghmisheh S, et al. Am J Cancer Res. 2023 Jan 15;13(1):176-189. eCollection 2023. Am J Cancer Res. 2023. PMID: 36777515 Free PMC article.
CASZ1 bound to the ITGAV promoter and transcriptionally regulated ITGAV expression. Our findings demonstrate that CASZ1 plays an oncogenic role in lung cancer and that CASZ1 promotes lung cancer migration, invasion and metastasis is mediated by ITGA …
CASZ1 bound to the ITGAV promoter and transcriptionally regulated ITGAV expression. Our findings demonstrate that CASZ1 plays …
Yin Yang 1 regulates ITGAV and ITGB1, contributing to improved prognosis of colorectal cancer.
Sato N, Sakai N, Furukawa K, Takayashiki T, Kuboki S, Takano S, Ohira G, Matsubara H, Ohtsuka M. Sato N, et al. Oncol Rep. 2022 May;47(5):87. doi: 10.3892/or.2022.8298. Epub 2022 Mar 10. Oncol Rep. 2022. PMID: 35266011 Free PMC article.
However, its biological role and clinical impact in colorectal cancer (CRC) remain unclear. In the present study, the function and underlying molecular mechanisms of YY1 in CRC progression were investigated. ...Western blotting and IHC confirmed YY1 expression to be negati …
However, its biological role and clinical impact in colorectal cancer (CRC) remain unclear. In the present study, the function and un …
IL-32gamma suppresses lung cancer stem cell growth via inhibition of ITGAV-mediated STAT5 pathway.
Lee YS, Kim KC, Mongre RK, Kim JY, Kim YR, Choi DY, Song S, Yun J, Han SB, Yoon DY, Hong JT. Lee YS, et al. Cell Death Dis. 2019 Jul 1;10(7):506. doi: 10.1038/s41419-019-1737-4. Cell Death Dis. 2019. PMID: 31263095 Free PMC article.
The cancer stem cells (CSCs) are thought to be responsible for cancer initiation, recurrence, and metastasis via a multifactorial process. ...Web-based gene network analysis showed that IL-32 is correlated with ITGAV, an integrin gene. Our result revealed tha …
The cancer stem cells (CSCs) are thought to be responsible for cancer initiation, recurrence, and metastasis via a multifactor …
Machine learning with imaging features to predict the expression of ITGAV, which is a poor prognostic factor derived from transcriptome analysis in pancreatic cancer.
Iwatate Y, Yokota H, Hoshino I, Ishige F, Kuwayama N, Itami M, Mori Y, Chiba S, Arimitsu H, Yanagibashi H, Takayama W, Uno T, Lin J, Nakamura Y, Tatsumi Y, Shimozato O, Nagase H. Iwatate Y, et al. Int J Oncol. 2022 May;60(5):60. doi: 10.3892/ijo.2022.5350. Epub 2022 Apr 8. Int J Oncol. 2022. PMID: 35419611 Free PMC article.
The ITGAV prediction model showed some detectability (AUC=0.697), and the predicted ITGAV high-expression group was also associated with a worse prognosis (P=0.048). In conclusion, radiogenomics predicted the expression of ITGAV in pancreatic cancer, a …
The ITGAV prediction model showed some detectability (AUC=0.697), and the predicted ITGAV high-expression group was also assoc …
Cancer genes disfavoring T cell immunity identified via integrated systems approach.
Kishton RJ, Patel SJ, Decker AE, Vodnala SK, Cam M, Yamamoto TN, Patel Y, Sukumar M, Yu Z, Ji M, Henning AN, Gurusamy D, Palmer DC, Stefanescu RA, Girvin AT, Lo W, Pasetto A, Malekzadeh P, Deniger DC, Wood KC, Sanjana NE, Restifo NP. Kishton RJ, et al. Cell Rep. 2022 Aug 2;40(5):111153. doi: 10.1016/j.celrep.2022.111153. Cell Rep. 2022. PMID: 35926468 Free PMC article.
Adoptive T cell therapies (ACT) have been curative for a limited number of cancer patients. The sensitization of cancer cells to T cell killing may expand the benefit of these therapies for more patients. To this end, we use a three-step approach to identify canc …
Adoptive T cell therapies (ACT) have been curative for a limited number of cancer patients. The sensitization of cancer cells …
Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform.
Rai A, Fang H, Claridge B, Simpson RJ, Greening DW. Rai A, et al. J Extracell Vesicles. 2021 Nov;10(13):e12164. doi: 10.1002/jev2.12164. J Extracell Vesicles. 2021. PMID: 34817906 Free PMC article.
Using a membrane impermeant derivative of biotin to capture surface proteins coupled to mass spectrometry analysis, we show that out of 4143 proteins identified in density-gradient purified L-EVs (1.07-1.11 g/mL, from multiple cancer cell lines), 961 proteins are surface a …
Using a membrane impermeant derivative of biotin to capture surface proteins coupled to mass spectrometry analysis, we show that out of 4143 …
180 results