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A multi-scale map of protein assemblies in the DNA damage response.
Kratz A, Kim M, Kelly MR, Zheng F, Koczor CA, Li J, Ono K, Qin Y, Churas C, Chen J, Pillich RT, Park J, Modak M, Collier R, Licon K, Pratt D, Sobol RW, Krogan NJ, Ideker T. Kratz A, et al. Among authors: ideker t. Cell Syst. 2023 Jun 21;14(6):447-463.e8. doi: 10.1016/j.cels.2023.04.007. Epub 2023 May 22. Cell Syst. 2023. PMID: 37220749 Free article.
Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation.
Ford K, Munson BP, Fong SH, Panwala R, Chu WK, Rainaldi J, Plongthongkum N, Arunachalam V, Kostrowicki J, Meluzzi D, Kreisberg JF, Jensen-Pergakes K, VanArsdale T, Paul T, Tamayo P, Zhang K, Bienkowska J, Mali P, Ideker T. Ford K, et al. Among authors: ideker t. Sci Rep. 2023 May 11;13(1):7678. doi: 10.1038/s41598-023-33329-2. Sci Rep. 2023. PMID: 37169829 Free PMC article.
On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w.
Van Oss SB, Parikh SB, Castilho Coelho N, Wacholder A, Belashov I, Zdancewicz S, Michaca M, Xu J, Kang YP, Ward NP, Yoon SJ, McCourt KM, McKee J, Ideker T, VanDemark AP, DeNicola GM, Carvunis AR. Van Oss SB, et al. Among authors: ideker t. J Biol Chem. 2022 Dec;298(12):102697. doi: 10.1016/j.jbc.2022.102697. Epub 2022 Nov 13. J Biol Chem. 2022. PMID: 36379252 Free PMC article.
281 results