Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 1
1987 4
1988 2
1989 5
1990 9
1991 39
1992 68
1993 75
1994 131
1995 163
1996 137
1997 156
1998 118
1999 131
2000 153
2001 153
2002 209
2003 186
2004 186
2005 207
2006 155
2007 74
2008 103
2009 97
2010 86
2011 82
2012 95
2013 108
2014 109
2015 109
2016 90
2017 93
2018 74
2019 105
2020 103
2021 93
2022 77
2023 60
2024 26

Text availability

Article attribute

Article type

Publication date

Search Results

3,628 results

Results by year

Filters applied: . Clear all
Page 1
Single-cell RNA sequencing identifies an Il1rn(+)/Trem1(+) macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection.
Liu X, Chen W, Zhu G, Yang H, Li W, Luo M, Shu C, Zhou Z. Liu X, et al. Cell Discov. 2022 Feb 8;8(1):11. doi: 10.1038/s41421-021-00362-2. Cell Discov. 2022. PMID: 35132073 Free PMC article.
., Lyve1(+) resident-like, Cd74(high) antigen-presenting, and Il1rn(+)/Trem1(+) pro-inflammatory macrophages. In both mice and humans, the pro-inflammatory macrophage subpopulation was found to represent the predominant source of most detrimental molecules. Suppression of …
., Lyve1(+) resident-like, Cd74(high) antigen-presenting, and Il1rn(+)/Trem1(+) pro-inflammatory macrophages. In both mice and humans …
IL1RN promotes osteoblastic differentiation via interacting with ITGB3 in osteoporosis.
Zou Z, Liu R, Wang Y, Xing Y, Shi Z, Wang K, Dong D. Zou Z, et al. Acta Biochim Biophys Sin (Shanghai). 2021 Mar 2;53(3):294-303. doi: 10.1093/abbs/gmaa174. Acta Biochim Biophys Sin (Shanghai). 2021. PMID: 33493267 Free article.
Although it was recently reported that IL1RN is involved in osteoblast differentiation, the role of IL1RN in osteogenesis remains unclear. ...To verify the exact role of IL1RN in osteoblast differentiation, we established IL1RN-downregulated/upregulate …
Although it was recently reported that IL1RN is involved in osteoblast differentiation, the role of IL1RN in osteogenesis rema …
The levels of IL1RN is a factor influencing the onset of rheumatoid arthritis in non-alcoholic fatty liver disease.
Gu J, Xu J, Jiao A, Gao Z, Zhang C, Cai N, Xia S, Li J, Wang Z, Chen G, Liu X, Chen Y. Gu J, et al. Int Immunopharmacol. 2024 Feb 15;128:111528. doi: 10.1016/j.intimp.2024.111528. Epub 2024 Jan 18. Int Immunopharmacol. 2024. PMID: 38241845
In this study, based on immune phenotypes, intercellular communication activities, and clinical manifestations of NAFLD patients, IL1RN was identified as a central pro-inflammatory factor. Subsequently, potential downstream biological pathways of IL1RN in liver tiss …
In this study, based on immune phenotypes, intercellular communication activities, and clinical manifestations of NAFLD patients, IL1RN …
IL1RN mediates the suppressive effect of methionine deprivation on glioma proliferation.
Wang K, Liu H, Liu J, Wang X, Teng L, Zhang J, Liu Y, Yao Y, Wang J, Qu Y, Chen X, Peng F, Liu H, Wang N, Zhong Y, Hou X, Jiang H, Beylerli O, Liao X, Zhang X, Zhang X, Zhang X, Zhao S. Wang K, et al. Cancer Lett. 2019 Jul 10;454:146-157. doi: 10.1016/j.canlet.2019.04.004. Epub 2019 Apr 10. Cancer Lett. 2019. PMID: 30978442
Here we demonstrated that methionine deprivation inhibited glioma cell proliferation via downregulating interleukin 1 receptor antagonist (IL1RN) both in vitro and in vivo, methionine deprivation or knocking down IL1RN induced glioma cell cycle arrest. Moreover, we …
Here we demonstrated that methionine deprivation inhibited glioma cell proliferation via downregulating interleukin 1 receptor antagonist ( …
IL1RN Polymorphisms Are Associated with a Decreased Risk of Esophageal Cancer Susceptibility in a Chinese Population.
Wang T, Feng Y, Zhao Z, Wang H, Zhang Y, Zhang Y, Liu H, Jin T, Liu Q. Wang T, et al. Chemotherapy. 2019;64(1):28-35. doi: 10.1159/000496400. Epub 2019 Apr 17. Chemotherapy. 2019. PMID: 30995661
BACKGROUND: Recent evidence suggested that IL1RN (interleukin-1 receptor antagonist) polymorphisms increased the susceptibility to cancers. The present study aimed to evaluate whether IL1RN was related to esophageal cancer susceptibility in a Northwest Han Chinese p …
BACKGROUND: Recent evidence suggested that IL1RN (interleukin-1 receptor antagonist) polymorphisms increased the susceptibility to ca …
Lack of Association Between the IL1B (-511 and +3954), IL1RN VNTR Polymorphisms and Tuberculosis Risk: A Meta-analysis.
Huang QP, Liao N, Zhao H, Chen ML, Xie ZF. Huang QP, et al. Lung. 2015 Dec;193(6):985-92. doi: 10.1007/s00408-015-9796-5. Epub 2015 Sep 2. Lung. 2015. PMID: 26330006 Review.
Our results did not indicate any association of the IL1B (-511 and +3954) and IL1RN VNTR polymorphisms with TB risk in the overall populations. ...CONCLUSIONS: Our results indicate there is a lack of association between the IL1B (-511 and +3954), IL1RN VNTR polymorp …
Our results did not indicate any association of the IL1B (-511 and +3954) and IL1RN VNTR polymorphisms with TB risk in the overall po …
Deficiency of Interleukin-1 Receptor Antagonist (DIRA): Report of the First Indian Patient and a Novel Deletion Affecting IL1RN.
Mendonca LO, Malle L, Donovan FX, Chandrasekharappa SC, Montealegre Sanchez GA, Garg M, Tedgard U, Castells M, Saini SS, Dutta S, Goldbach-Mansky R, Suri D, Jesus AA. Mendonca LO, et al. J Clin Immunol. 2017 Jul;37(5):445-451. doi: 10.1007/s10875-017-0399-1. Epub 2017 May 15. J Clin Immunol. 2017. PMID: 28503715 Free PMC article. Review.
PURPOSE: Deficiency of interleukin-1 receptor antagonist (DIRA) is a rare life-threatening autoinflammatory disease caused by autosomal recessive mutations in IL1RN. DIRA presents clinically with early onset generalized pustulosis, multifocal osteomyelitis, and elevation o …
PURPOSE: Deficiency of interleukin-1 receptor antagonist (DIRA) is a rare life-threatening autoinflammatory disease caused by autosomal rece …
IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis.
Wang Q, Huang X, Zhou S, Ding Y, Wang H, Jiang W, Xu M. Wang Q, et al. Int J Genomics. 2022 Nov 29;2022:2723264. doi: 10.1155/2022/2723264. eCollection 2022. Int J Genomics. 2022. PMID: 36483329 Free PMC article.
The Molecular Complex Detection (MCODE), Biological Network Gene Oncology (BiNGO) plug-in in Cytoscape, was applied to further screen the DEGs to obtain 15 seed genes, which were IL1RN, GALNT12, ADH6, SCN7A, CXCL1, FGF18, SOX9, ACACB, PRRX1, MZB1, SLC22A3, CNNM4, LY6E, IFI …
The Molecular Complex Detection (MCODE), Biological Network Gene Oncology (BiNGO) plug-in in Cytoscape, was applied to further screen the DE …
The transcription factor ELF4 alleviates inflammatory bowel disease by activating IL1RN transcription, suppressing inflammatory TH17 cell activity, and inducing macrophage M2 polarization.
Cao M, Chen P, Peng B, Cheng Y, Xie J, Hou Z, Chen H, Ye L, Li H, Wang H, Ren L, Xiong L, Geng L, Gong S. Cao M, et al. Front Immunol. 2023 Nov 6;14:1270411. doi: 10.3389/fimmu.2023.1270411. eCollection 2023. Front Immunol. 2023. PMID: 38022496 Free PMC article.
ELF4 overexpression reduced mouse intestinal inflammation. ELF4 activated IL1RN transcription in bioinformatics and in vitro tests. ELF4 promoted IL1RN transcription and macrophage M2 polarization to limit intestinal epithelial cell death and inflammation and reduce …
ELF4 overexpression reduced mouse intestinal inflammation. ELF4 activated IL1RN transcription in bioinformatics and in vitro tests. E …
3,628 results