Single-cell RNA sequencing defines disease-specific differences between chronic nodular prurigo and atopic dermatitis.
Alkon N, Assen FP, Arnoldner T, Bauer WM, Medjimorec MA, Shaw LE, Rindler K, Holzer G, Weber P, Weninger W, Freystätter C, Chennareddy S, Kinaciyan T, Farlik M, Jonak C, Griss J, Bangert C, Brunner PM.
Alkon N, et al.
J Allergy Clin Immunol. 2023 Aug;152(2):420-435. doi: 10.1016/j.jaci.2023.04.019. Epub 2023 May 18.
J Allergy Clin Immunol. 2023.
PMID: 37210042
Conversely, CNPG showed signatures of extracellular matrix organization, collagen synthesis, and fibrosis, including a unique population of CXCL14(-)IL24(+) secretory papillary fibroblasts. Besides known itch mediators such as IL31 and oncostatin M, we also detected increa …
Conversely, CNPG showed signatures of extracellular matrix organization, collagen synthesis, and fibrosis, including a unique population of …