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Year Number of Results
1987 1
2003 1
2005 2
2006 4
2007 19
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2010 109
2011 143
2012 220
2013 286
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5,623 results

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Page 1
IL33 and Mast Cells-The Key Regulators of Immune Responses in Gastrointestinal Cancers?
Eissmann MF, Buchert M, Ernst M. Eissmann MF, et al. Front Immunol. 2020 Jul 3;11:1389. doi: 10.3389/fimmu.2020.01389. eCollection 2020. Front Immunol. 2020. PMID: 32719677 Free PMC article. Review.
Thus, the balance between tumor suppressing and tumor promoting activities of IL33 are highly context dependent, and most likely dictated by the mixture of cell types responding to IL33. ...We discuss how these opposing responses affect the therapeutic potential of …
Thus, the balance between tumor suppressing and tumor promoting activities of IL33 are highly context dependent, and most likely dict …
Fibroblast-Derived IL33 Facilitates Breast Cancer Metastasis by Modifying the Immune Microenvironment and Driving Type 2 Immunity.
Shani O, Vorobyov T, Monteran L, Lavie D, Cohen N, Raz Y, Tsarfaty G, Avivi C, Barshack I, Erez N. Shani O, et al. Cancer Res. 2020 Dec 1;80(23):5317-5329. doi: 10.1158/0008-5472.CAN-20-2116. Epub 2020 Oct 6. Cancer Res. 2020. PMID: 33023944 Free PMC article.
Importantly, targeting of IL33 in vivo resulted in inhibition of lung metastasis and significant attenuation of immune cell recruitment and type 2 immunity. These findings demonstrate a key function of IL33 in facilitating lung metastatic relapse by modulating the i …
Importantly, targeting of IL33 in vivo resulted in inhibition of lung metastasis and significant attenuation of immune cell recruitme …
IL33/ST2 Axis in Diabetic Kidney Disease: A Literature Review.
Tonacci A, Quattrocchi P, Gangemi S. Tonacci A, et al. Medicina (Kaunas). 2019 Feb 14;55(2):50. doi: 10.3390/medicina55020050. Medicina (Kaunas). 2019. PMID: 30769901 Free PMC article. Review.
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. ...
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune d …
The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration.
Cosway EJ, James KD, White AJ, Parnell SM, Bacon A, McKenzie ANJ, Jenkinson WE, Anderson G. Cosway EJ, et al. Nat Commun. 2023 Nov 8;14(1):7201. doi: 10.1038/s41467-023-43072-x. Nat Commun. 2023. PMID: 37938566 Free PMC article.
Here, we show the alarmin interleukin (IL) 33 is a product of Sca1(+) thymic mesenchyme both necessary and sufficient for thymus regeneration via a type 2 innate immune network. IL33 stimulates expansion of IL5-producing type 2 innate lymphoid cells (ILC2), which triggers …
Here, we show the alarmin interleukin (IL) 33 is a product of Sca1(+) thymic mesenchyme both necessary and sufficient for thymus regeneratio …
IL33 in rheumatoid arthritis: potential contribution to pathogenesis.
Macedo RB, Kakehasi AM, Melo de Andrade MV. Macedo RB, et al. Rev Bras Reumatol Engl Ed. 2016 Sep-Oct;56(5):451-457. doi: 10.1016/j.rbre.2016.03.009. Epub 2016 Jun 1. Rev Bras Reumatol Engl Ed. 2016. PMID: 27692395 Free article. Review. English, Portuguese.
A better understanding of the inflammatory mechanisms of rheumatoid arthritis and the development of biological therapy revolutionized its treatment, enabling an interference in the synovitis - structural damage - functional disability cycle. Interleukin 33 was rece …
A better understanding of the inflammatory mechanisms of rheumatoid arthritis and the development of biological therapy revolutionized its t …
Interleukin-33 in health and disease.
Liew FY, Girard JP, Turnquist HR. Liew FY, et al. Nat Rev Immunol. 2016 Nov;16(11):676-689. doi: 10.1038/nri.2016.95. Epub 2016 Sep 19. Nat Rev Immunol. 2016. PMID: 27640624 Review.
Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, activating T helper 2 (T(H)2) cells and mast cells. ...
Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, acti …
IL-33/ST2 axis in autoimmune disease.
Shakerian L, Kolahdooz H, Garousi M, Keyvani V, Kamal Kheder R, Abdulsattar Faraj T, Yazdanpanah E, Esmaeili SA. Shakerian L, et al. Cytokine. 2022 Oct;158:156015. doi: 10.1016/j.cyto.2022.156015. Epub 2022 Aug 27. Cytokine. 2022. PMID: 36041312 Review.
Interleukin-33 (IL-33) is a member of the IL-1 family and plays an ambivalent role in autoimmune diseases. ...
Interleukin-33 (IL-33) is a member of the IL-1 family and plays an ambivalent role in autoimmune diseases. ...
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues.
Widjaja AA, Chothani S, Viswanathan S, Goh JWT, Lim WW, Cook SA. Widjaja AA, et al. Int J Mol Sci. 2022 Aug 10;23(16):8900. doi: 10.3390/ijms23168900. Int J Mol Sci. 2022. PMID: 36012165 Free PMC article.
RNA sequencing over a time course of IL11 stimulation revealed a robust but short-lived transcriptional response that was enriched for gene set hallmarks of inflammation and characterized by the upregulation of SERPINB2, TNFRSF18, Interleukin 33 (IL33), CCL20 …
RNA sequencing over a time course of IL11 stimulation revealed a robust but short-lived transcriptional response that was enriched for gene …
IL-33/ST2 Axis in Organ Fibrosis.
Kotsiou OS, Gourgoulianis KI, Zarogiannis SG. Kotsiou OS, et al. Front Immunol. 2018 Oct 24;9:2432. doi: 10.3389/fimmu.2018.02432. eCollection 2018. Front Immunol. 2018. PMID: 30405626 Free PMC article. Review.
Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). ...
Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). .. …
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity.
Nguyen PT, Dorman LC, Pan S, Vainchtein ID, Han RT, Nakao-Inoue H, Taloma SE, Barron JJ, Molofsky AB, Kheirbek MA, Molofsky AV. Nguyen PT, et al. Cell. 2020 Jul 23;182(2):388-403.e15. doi: 10.1016/j.cell.2020.05.050. Epub 2020 Jul 1. Cell. 2020. PMID: 32615087 Free PMC article.
Here, we define a molecular interaction between neurons and microglia that drives experience-dependent synapse remodeling in the hippocampus. We find that the cytokine interleukin-33 (IL-33) is expressed by adult hippocampal neurons in an experience-dependent manner …
Here, we define a molecular interaction between neurons and microglia that drives experience-dependent synapse remodeling in the hippocampus …
5,623 results