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Penetrating cations enhance uncoupling activity of anionic protonophores in mitochondria.
Antonenko YN, Khailova LS, Knorre DA, Markova OV, Rokitskaya TI, Ilyasova TM, Severina II, Kotova EA, Karavaeva YE, Prikhodko AS, Severin FF, Skulachev VP. Antonenko YN, et al. Among authors: ilyasova tm. PLoS One. 2013 Apr 23;8(4):e61902. doi: 10.1371/journal.pone.0061902. Print 2013. PLoS One. 2013. PMID: 23626747 Free PMC article.
A short-chain alkyl derivative of Rhodamine 19 acts as a mild uncoupler of mitochondria and a neuroprotector.
Khailova LS, Silachev DN, Rokitskaya TI, Avetisyan AV, Lyamsaev KG, Severina II, Il'yasova TM, Gulyaev MV, Dedukhova VI, Trendeleva TA, Plotnikov EY, Zvyagilskaya RA, Chernyak BV, Zorov DB, Antonenko YN, Skulachev VP. Khailova LS, et al. Biochim Biophys Acta. 2014 Oct;1837(10):1739-47. doi: 10.1016/j.bbabio.2014.07.006. Epub 2014 Jul 16. Biochim Biophys Acta. 2014. PMID: 25038514 Free article.
In search of novel highly active mitochondria-targeted antioxidants: thymoquinone and its cationic derivatives.
Severina II, Severin FF, Korshunova GA, Sumbatyan NV, Ilyasova TM, Simonyan RA, Rogov AG, Trendeleva TA, Zvyagilskaya RA, Dugina VB, Domnina LV, Fetisova EK, Lyamzaev KG, Vyssokikh MY, Chernyak BV, Skulachev MV, Skulachev VP, Sadovnichii VA. Severina II, et al. Among authors: ilyasova tm. FEBS Lett. 2013 Jun 27;587(13):2018-24. doi: 10.1016/j.febslet.2013.04.043. Epub 2013 May 10. FEBS Lett. 2013. PMID: 23665033 Free article. Review.