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Age-related changes in the elastic properties and thickness of human facial skin.
Takema Y, Yorimoto Y, Kawai M, Imokawa G. Takema Y, et al. Among authors: imokawa g. Br J Dermatol. 1994 Nov;131(5):641-8. doi: 10.1111/j.1365-2133.1994.tb04975.x. Br J Dermatol. 1994. PMID: 7999594
Deficient production of hexadecenoic acid in the skin is associated in part with the vulnerability of atopic dermatitis patients to colonization by Staphylococcus aureus.
Takigawa H, Nakagawa H, Kuzukawa M, Mori H, Imokawa G. Takigawa H, et al. Among authors: imokawa g. Dermatology. 2005;211(3):240-8. doi: 10.1159/000087018. Dermatology. 2005. PMID: 16205069
Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging I: reduced skin elasticity, highly associated with enhanced dermal elastase activity, triggers wrinkling and sagging.
Imokawa G, Ishida K. Imokawa G, et al. Int J Mol Sci. 2015 Apr 8;16(4):7753-75. doi: 10.3390/ijms16047753. Int J Mol Sci. 2015. PMID: 25856675 Free PMC article. Review.
Neprilysin is identical to skin fibroblast elastase: its role in skin aging and UV responses.
Morisaki N, Moriwaki S, Sugiyama-Nakagiri Y, Haketa K, Takema Y, Imokawa G. Morisaki N, et al. Among authors: imokawa g. J Biol Chem. 2010 Dec 17;285(51):39819-27. doi: 10.1074/jbc.M110.161547. Epub 2010 Sep 28. J Biol Chem. 2010. PMID: 20876573 Free PMC article.
Mechanism of UVB-induced wrinkling of the skin: paracrine cytokine linkage between keratinocytes and fibroblasts leading to the stimulation of elastase.
Imokawa G. Imokawa G. J Investig Dermatol Symp Proc. 2009 Aug;14(1):36-43. doi: 10.1038/jidsymp.2009.11. J Investig Dermatol Symp Proc. 2009. PMID: 19675551 Review.
Inhibition of ultraviolet-B-induced wrinkle formation by an elastase-inhibiting herbal extract: implication for the mechanism underlying elastase-associated wrinkles.
Tsukahara K, Nakagawa H, Moriwaki S, Takema Y, Fujimura T, Imokawa G. Tsukahara K, et al. Among authors: imokawa g. Int J Dermatol. 2006 Apr;45(4):460-8. doi: 10.1111/j.1365-4632.2006.02557.x. Int J Dermatol. 2006. PMID: 16650179
Crucial role of fibroblast integrins alpha2 and beta1 in maintaining the structural and mechanical properties of the skin.
Fujimura T, Moriwaki S, Imokawa G, Takema Y. Fujimura T, et al. Among authors: imokawa g. J Dermatol Sci. 2007 Jan;45(1):45-53. doi: 10.1016/j.jdermsci.2006.09.012. Epub 2006 Nov 21. J Dermatol Sci. 2007. PMID: 17118629
Biosynthesis of acylceramide in murine epidermis: characterization by inhibition of glucosylation and deglucosylation, and by substrate specificity.
Takagi Y, Nakagawa H, Matsuo N, Nomura T, Takizawa M, Imokawa G. Takagi Y, et al. Among authors: imokawa g. J Invest Dermatol. 2004 Mar;122(3):722-9. doi: 10.1111/j.0022-202X.2004.22307.x. J Invest Dermatol. 2004. PMID: 15086559
Paracrine cytokine mechanisms underlying the hyperpigmentation of seborrheic keratosis in covered skin areas.
Takenaka Y, Hoshino Y, Nakajima H, Hayashi N, Kawashima M, Imokawa G. Takenaka Y, et al. Among authors: imokawa g. J Dermatol. 2013 Jul;40(7):533-42. doi: 10.1111/1346-8138.12178. Epub 2013 May 10. J Dermatol. 2013. PMID: 23662587
Epithelial-mesenchymal interaction mechanisms leading to the over-expression of neprilysin are involved in the UVB-induced formation of wrinkles in the skin.
Imokawa G. Imokawa G. Exp Dermatol. 2016 Aug;25 Suppl 3:2-13. doi: 10.1111/exd.13083. Exp Dermatol. 2016. PMID: 27539896 Review.
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