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A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma.
Borghi V, Bastia E, Guzzetta M, Chiroli V, Toris CB, Batugo MR, Carreiro ST, Chong WK, Gale DC, Kucera DJ, Jia L, Prasanna G, Ongini E, Krauss AH, Impagnatiello F. Borghi V, et al. Among authors: impagnatiello f. J Ocul Pharmacol Ther. 2010 Apr;26(2):125-32. doi: 10.1089/jop.2009.0120. J Ocul Pharmacol Ther. 2010. PMID: 20415621
Enhanced oxygen saturation in optic nerve head of non-human primate eyes following the intravitreal injection of NCX 434, an innovative nitric oxide-donating glucocorticoid.
Khoobehi B, Chiroli V, Ronchetti D, Miglietta D, Thompson H, Ongini E, Impagnatiello F. Khoobehi B, et al. Among authors: impagnatiello f. J Ocul Pharmacol Ther. 2011 Apr;27(2):115-21. doi: 10.1089/jop.2010.0150. Epub 2011 Mar 17. J Ocul Pharmacol Ther. 2011. PMID: 21413860 Free PMC article.
Repeated Dosing with NCX1404, a Nitric Oxide-Donating Pregabalin, Re-establishes Normal Nociceptive Responses in Mice with Streptozotocin-Induced Painful Diabetic Neuropathy.
Varani K, Vincenzi F, Targa M, Ravani A, Bastia E, Storoni L, Brambilla S, Almirante N, Impagnatiello F. Varani K, et al. Among authors: impagnatiello f. J Pharmacol Exp Ther. 2016 May;357(2):240-7. doi: 10.1124/jpet.115.230193. Epub 2016 Feb 23. J Pharmacol Exp Ther. 2016. PMID: 26907623
47 results