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The following term was not found in PubMed: pseudogermanica
Page 1
Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review.
Malarz J, Michalska K, Stojakowska A. Malarz J, et al. Molecules. 2024 Apr 27;29(9):2014. doi: 10.3390/molecules29092014. Molecules. 2024. PMID: 38731504 Review.
Polyphenols next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological activity of medicinal plants from the subtribe (Blumea spp., Dittrichia spp., Inula spp., Pulicaria spp. and others). Recent decades …
Polyphenols next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological …
The Inhibition Activity of Natural Methoxyflavonoid from Inula britannica on Soluble Epoxide Hydrolase and NO Production in RAW264.7 Cells.
Kim JH, Han KS, Lee ES, Kim YG, Kim YI, Cho BO, Lee IS. Kim JH, et al. Int J Mol Sci. 2024 Apr 15;25(8):4357. doi: 10.3390/ijms25084357. Int J Mol Sci. 2024. PMID: 38673942 Free PMC article.
We identify an inhibitor able to suppress sEH and thus NO production. Five flavonoids 1-5 isolated from Inula britannica flowers were evaluated for their abilities to inhibit sEH with IC(50) values of 12.1 0.1 to 62.8 1.8 M and for their effects on enzyme kinetics. ...
We identify an inhibitor able to suppress sEH and thus NO production. Five flavonoids 1-5 isolated from Inula britannica flowers were …
Inubritantrimers A-D: Trimerized Sesquiterpenoid [4 + 2] Adducts Featuring a Distinctive Spiro-Polycyclic Scaffold from Inula britannica.
Guo C, Qi RY, Ren JY, Xu DD, Zhang Q, Gao JM, Tang JJ. Guo C, et al. J Org Chem. 2024 Apr 5;89(7):5029-5037. doi: 10.1021/acs.joc.4c00248. Epub 2024 Mar 26. J Org Chem. 2024. PMID: 38531374
Inubritantrimer A (1), a trace trimerized sesquiterpenoid [4 + 2] adduct featuring an unusual exo-exo type spiro-polycyclic scaffold, together with three new endo-exo [4 + 2] adducts, inubritantrimers B-D (2-4), were discovered from the flowers of Inula britannica. Their s …
Inubritantrimer A (1), a trace trimerized sesquiterpenoid [4 + 2] adduct featuring an unusual exo-exo type spiro-polycyclic scaffold, togeth …
Sesquiterpene Acids and Lactones from Inula Confertiflora with their Antibacterial Activities.
Ahmed BH, Desta MA, Wami AA, Beyene GT, Bedane KG. Ahmed BH, et al. Chem Biodivers. 2024 Mar 12:e202400265. doi: 10.1002/cbdv.202400265. Online ahead of print. Chem Biodivers. 2024. PMID: 38470349
The phytochemical investigation of the leaves of Inula confertiflora, a medicinal plant endemic to Ethiopia, led to the isolation of 15 terpenoids; 1beta-hydroxy-alpha-costic acid (1), 3alpha-hydroxycostic acid (2), isotelekin (3), asperilin (4), carabrone (5), carpesiolin …
The phytochemical investigation of the leaves of Inula confertiflora, a medicinal plant endemic to Ethiopia, led to the isolation of …
Inulae Flos has Anti-Depressive Effects by Suppressing Neuroinflammation and Recovering Dysfunction of HPA-axis.
Kim JS, Kim JH, Eo H, Ju IG, Son SR, Kim JW, Jang DS, Oh MS. Kim JS, et al. Mol Neurobiol. 2024 Mar 8. doi: 10.1007/s12035-024-04094-8. Online ahead of print. Mol Neurobiol. 2024. PMID: 38457106
Neuroinflammation and the hypothalamic-pituitary-adrenal (HPA) axis are pivotal factors in depression. Inulae Flos (IF), the flower of Inula japonica Thunb, is known for its antioxidant and anti-inflammatory effects. ...
Neuroinflammation and the hypothalamic-pituitary-adrenal (HPA) axis are pivotal factors in depression. Inulae Flos (IF), the flower o …
Integrated Pharmaco-Bioinformatics Approaches and Experimental Verification To Explore the Effect of Britanin on Nonalcoholic Fatty Liver Disease.
Dou C, Zhu H, Xie X, Huang C, Cao C. Dou C, et al. ACS Omega. 2024 Feb 9;9(7):8274-8286. doi: 10.1021/acsomega.3c08968. eCollection 2024 Feb 20. ACS Omega. 2024. PMID: 38405493 Free PMC article.
Nonalcoholic fatty liver disease (NAFLD) is a prevalent global liver disorder, posing substantial health risks. Britanin, a bioactive sesquiterpene lactone extracted from Inula japonica, has demonstrated antidiabetic, hypolipidemic, and hepatoprotective attributes. ...
Nonalcoholic fatty liver disease (NAFLD) is a prevalent global liver disorder, posing substantial health risks. Britanin, a bioactive sesqui …
Gaillardin exerts potent antileukemic effects on HL-60 cells and intensifies arsenic trioxide cytotoxicity: Providing new insight into sesquiterpene lactones in leukaemia treatment.
Noormohamadi H, Hamzeloo-Moghadam M, Bashash D, Kargar M, Izadirad M, Hasanpour SZ, Gharehbaghian A. Noormohamadi H, et al. Clin Exp Pharmacol Physiol. 2024 Apr;51(4):e13847. doi: 10.1111/1440-1681.13847. Clin Exp Pharmacol Physiol. 2024. PMID: 38382534
Numerous studies have proven the cytotoxic properties of Gaillardin, one of the Inula oculus-christi-derived sesquiterpene lactones. Due to the adverse effects of arsenic trioxide on the high-risk subgroup of APL patients, we aimed to assess the cytotoxic effect of Gaillar …
Numerous studies have proven the cytotoxic properties of Gaillardin, one of the Inula oculus-christi-derived sesquiterpene lactones. …
Anti-Fibrosis Effect of Panax ginseng and Inula japonica Formula in Human Pulmonary Fibroblasts.
Jung Y, Yim NH, Lee SM, Cho WK, Cha MH, Ma JY. Jung Y, et al. Nutrients. 2024 Jan 22;16(2):319. doi: 10.3390/nu16020319. Nutrients. 2024. PMID: 38276557 Free PMC article.
Panax ginseng Meyer and Inula japonica Thunb. are well established in traditional medicine and are known for their therapeutic properties in managing a range of ailments such as diabetes, asthma, and cancer. ...
Panax ginseng Meyer and Inula japonica Thunb. are well established in traditional medicine and are known for their therapeutic proper …
Microwave-assisted extraction optimization of sesquiterpene lactones from Inula helenium roots: A sustainable approach to reduce energy consumption and carbon footprint.
Özcan FŞ, Dikmen H, Özcan N, Çetin Ö, Çelik M, Trendafilova A. Özcan FŞ, et al. Food Sci Nutr. 2023 Oct 13;12(1):255-267. doi: 10.1002/fsn3.3775. eCollection 2024 Jan. Food Sci Nutr. 2023. PMID: 38268885 Free PMC article.
Inula helenium roots are consumed as natural flavor components and raw or cooked as food, and their extracts are rich in sesquiterpene lactones such as alantolactone (AL) and isoalantolactone (IAL), which have recently attracted great attention due to their pharmacological …
Inula helenium roots are consumed as natural flavor components and raw or cooked as food, and their extracts are rich in sesquiterpen …
Gaillardin inhibits autophagy and induces apoptosis in MCF-7 breast cancer cells by regulating JAK/STAT pathway.
Rajabi S, Tahmasvand Z, Maresca M, Hamzeloo-Moghadam M. Rajabi S, et al. Mol Biol Rep. 2024 Jan 22;51(1):158. doi: 10.1007/s11033-023-09131-8. Mol Biol Rep. 2024. PMID: 38252203
BACKGROUND: Gaillardin is a potent anti-cancer sesquiterpene lactone found in Inula oculus-christi. AIM: The present study examined the effects of gaillardin on apoptosis and autophagy in the MCF-7 breast cancer cell line. ...
BACKGROUND: Gaillardin is a potent anti-cancer sesquiterpene lactone found in Inula oculus-christi. AIM: The present study examined t …
722 results