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Genomically recoded organisms expand biological functions.
Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ. Lajoie MJ, et al. Among authors: isaacs fj. Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459. Science. 2013. PMID: 24136966 Free PMC article.
Designed phosphoprotein recognition in Escherichia coli.
Sawyer N, Gassaway BM, Haimovich AD, Isaacs FJ, Rinehart J, Regan L. Sawyer N, et al. Among authors: isaacs fj. ACS Chem Biol. 2014 Nov 21;9(11):2502-7. doi: 10.1021/cb500658w. Epub 2014 Oct 6. ACS Chem Biol. 2014. PMID: 25272187 Free PMC article.
Recoded organisms engineered to depend on synthetic amino acids.
Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. Rovner AJ, et al. Among authors: isaacs fj. Nature. 2015 Feb 5;518(7537):89-93. doi: 10.1038/nature14095. Epub 2015 Jan 21. Nature. 2015. PMID: 25607356 Free PMC article.
Corrigendum: Recoded organisms engineered to depend on synthetic amino acids.
Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. Rovner AJ, et al. Among authors: isaacs fj. Nature. 2015 Nov 12;527(7577):264. doi: 10.1038/nature15537. Epub 2015 Sep 23. Nature. 2015. PMID: 26416756 No abstract available.
Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids.
Amiram M, Haimovich AD, Fan C, Wang YS, Aerni HR, Ntai I, Moonan DW, Ma NJ, Rovner AJ, Hong SH, Kelleher NL, Goodman AL, Jewett MC, Söll D, Rinehart J, Isaacs FJ. Amiram M, et al. Among authors: isaacs fj. Nat Biotechnol. 2015 Dec;33(12):1272-1279. doi: 10.1038/nbt.3372. Epub 2015 Nov 16. Nat Biotechnol. 2015. PMID: 26571098 Free PMC article.
67 results