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Control of heart rate by cAMP sensitivity of HCN channels.
Alig J, Marger L, Mesirca P, Ehmke H, Mangoni ME, Isbrandt D. Alig J, et al. Among authors: isbrandt d. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12189-94. doi: 10.1073/pnas.0810332106. Epub 2009 Jul 1. Proc Natl Acad Sci U S A. 2009. PMID: 19570998 Free PMC article.
Pacemaker activity and ionic currents in mouse atrioventricular node cells.
Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME. Marger L, et al. Among authors: isbrandt d. Channels (Austin). 2011 May-Jun;5(3):241-50. doi: 10.4161/chan.5.3.15264. Epub 2011 May 1. Channels (Austin). 2011. PMID: 21406959 Free PMC article.
Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.
Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME. Marger L, et al. Among authors: isbrandt d. Channels (Austin). 2011 May-Jun;5(3):251-61. doi: 10.4161/chan.5.3.15266. Epub 2011 May 1. Channels (Austin). 2011. PMID: 21406960 Free PMC article.
Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation.
Mesirca P, Alig J, Torrente AG, Müller JC, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, Fernandez A, Seniuk A, Engeland B, Singh J, Miquerol L, Ehmke H, Eschenhagen T, Nargeot J, Wickman K, Isbrandt D, Mangoni ME. Mesirca P, et al. Among authors: isbrandt d. Nat Commun. 2014 Aug 21;5:4664. doi: 10.1038/ncomms5664. Nat Commun. 2014. PMID: 25144323 Free PMC article.
The funny current in genetically modified mice.
DiFrancesco ML, Mesirca P, Bidaud I, Isbrandt D, Mangoni ME. DiFrancesco ML, et al. Among authors: isbrandt d. Prog Biophys Mol Biol. 2021 Nov;166:39-50. doi: 10.1016/j.pbiomolbio.2021.06.003. Epub 2021 Jun 12. Prog Biophys Mol Biol. 2021. PMID: 34129872 Review.
Pacemaker channel dysfunction in a patient with sinus node disease.
Schulze-Bahr E, Neu A, Friederich P, Kaupp UB, Breithardt G, Pongs O, Isbrandt D. Schulze-Bahr E, et al. Among authors: isbrandt d. J Clin Invest. 2003 May;111(10):1537-45. doi: 10.1172/JCI16387. J Clin Invest. 2003. PMID: 12750403 Free PMC article.
Treatment during a vulnerable developmental period rescues a genetic epilepsy.
Marguet SL, Le-Schulte VT, Merseburg A, Neu A, Eichler R, Jakovcevski I, Ivanov A, Hanganu-Opatz IL, Bernard C, Morellini F, Isbrandt D. Marguet SL, et al. Among authors: isbrandt d. Nat Med. 2015 Dec;21(12):1436-44. doi: 10.1038/nm.3987. Epub 2015 Nov 23. Nat Med. 2015. PMID: 26594844
71 results