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Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Fares I, et al. Among authors: iscove nn. Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337. Science. 2014. PMID: 25237102 Free PMC article.
Complementary and independent function for Hoxb4 and Bmi1 in HSC activity.
Faubert A, Chagraoui J, Mayotte N, Fréchette M, Iscove NN, Humphries RK, Sauvageau G. Faubert A, et al. Among authors: iscove nn. Cold Spring Harb Symp Quant Biol. 2008;73:555-64. doi: 10.1101/sqb.2008.73.030. Epub 2008 Nov 6. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19022763
Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Chan G, Cheung LS, Yang W, Milyavsky M, Sanders AD, Gu S, Hong WX, Liu AX, Wang X, Barbara M, Sharma T, Gavin J, Kutok JL, Iscove NN, Shannon KM, Dick JE, Neel BG, Braun BS. Chan G, et al. Among authors: iscove nn. Blood. 2011 Apr 21;117(16):4253-61. doi: 10.1182/blood-2010-11-319517. Epub 2011 Feb 25. Blood. 2011. PMID: 21398220 Free PMC article.
101 results