Ismail MA - Search Results

1

Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures.

Hunt RA, Munde M, Kumar A, Ismail MA, Farahat AA, Arafa RK, Say M, Batista-Parra A, Tevis D, Boykin DW, Wilson WD. Hunt RA, et al. Among authors: ismail ma. Nucleic Acids Res. 2011 May;39(10):4265-74. doi: 10.1093/nar/gkq1362. Epub 2011 Jan 25. Nucleic Acids Res. 2011. PMID: 21266485 Free PMC article.

2

Out-of-shape DNA minor groove binders: induced fit interactions of heterocyclic dications with the DNA minor groove.

Miao Y, Lee MP, Parkinson GN, Batista-Parra A, Ismail MA, Neidle S, Boykin DW, Wilson WD. Miao Y, et al. Among authors: ismail ma. Biochemistry. 2005 Nov 15;44(45):14701-8. doi: 10.1021/bi051791q. Biochemistry. 2005. PMID: 16274217

3

Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.

Munde M, Ismail MA, Arafa R, Peixoto P, Collar CJ, Liu Y, Hu L, David-Cordonnier MH, Lansiaux A, Bailly C, Boykin DW, Wilson WD. Munde M, et al. Among authors: ismail ma. J Am Chem Soc. 2007 Nov 7;129(44):13732-43. doi: 10.1021/ja074560a. Epub 2007 Oct 13. J Am Chem Soc. 2007. PMID: 17935330 Free PMC article.

4

DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site.

Munde M, Kumar A, Nhili R, Depauw S, David-Cordonnier MH, Ismail MA, Stephens CE, Farahat AA, Batista-Parra A, Boykin DW, Wilson WD. Munde M, et al. Among authors: ismail ma. J Mol Biol. 2010 Oct 8;402(5):847-64. doi: 10.1016/j.jmb.2010.08.018. Epub 2010 Aug 14. J Mol Biol. 2010. PMID: 20713062 Free PMC article.

5

Water-mediated binding of agents that target the DNA minor groove.

Liu Y, Kumar A, Depauw S, Nhili R, David-Cordonnier MH, Lee MP, Ismail MA, Farahat AA, Say M, Chackal-Catoen S, Batista-Parra A, Neidle S, Boykin DW, Wilson WD. Liu Y, et al. Among authors: ismail ma. J Am Chem Soc. 2011 Jul 6;133(26):10171-83. doi: 10.1021/ja202006u. Epub 2011 Jun 15. J Am Chem Soc. 2011. PMID: 21627167 Free PMC article.

6

Microscopic rearrangement of bound minor groove binders detected by NMR.

Rettig M, Germann MW, Ismail MA, Batista-Parra A, Munde M, Boykin DW, Wilson WD. Rettig M, et al. Among authors: ismail ma. J Phys Chem B. 2012 May 17;116(19):5620-7. doi: 10.1021/jp301143e. Epub 2012 May 2. J Phys Chem B. 2012. PMID: 22530735 Free PMC article.

7

The unusual monomer recognition of guanine-containing mixed sequence DNA by a dithiophene heterocyclic diamidine.

Munde M, Kumar A, Peixoto P, Depauw S, Ismail MA, Farahat AA, Paul A, Say MV, David-Cordonnier MH, Boykin DW, Wilson WD. Munde M, et al. Among authors: ismail ma. Biochemistry. 2014 Feb 25;53(7):1218-27. doi: 10.1021/bi401582t. Epub 2014 Feb 13. Biochemistry. 2014. PMID: 24495039 Free PMC article.

8

Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents.

Ismail MA, Batista-Parra A, Miao Y, Wilson WD, Wenzler T, Brun R, Boykin DW. Ismail MA, et al. Bioorg Med Chem. 2005 Dec 15;13(24):6718-26. doi: 10.1016/j.bmc.2005.07.024. Epub 2005 Aug 15. Bioorg Med Chem. 2005. PMID: 16099661

9

Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge.

White EW, Tanious F, Ismail MA, Reszka AP, Neidle S, Boykin DW, Wilson WD. White EW, et al. Among authors: ismail ma. Biophys Chem. 2007 Mar;126(1-3):140-53. doi: 10.1016/j.bpc.2006.06.006. Epub 2006 Jun 20. Biophys Chem. 2007. PMID: 16831507

10

Azaterphenyl diamidines as antileishmanial agents.

Hu L, Arafa RK, Ismail MA, Wenzler T, Brun R, Munde M, Wilson WD, Nzimiro S, Samyesudhas S, Werbovetz KA, Boykin DW. Hu L, et al. Among authors: ismail ma. Bioorg Med Chem Lett. 2008 Jan 1;18(1):247-51. doi: 10.1016/j.bmcl.2007.10.091. Epub 2007 Oct 30. Bioorg Med Chem Lett. 2008. PMID: 18006310

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