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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.
Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, Jurisicova A, Mak TW. Tomasini R, et al. Among authors: itie youten a. Genes Dev. 2008 Oct 1;22(19):2677-91. doi: 10.1101/gad.1695308. Epub 2008 Sep 19. Genes Dev. 2008. PMID: 18805989 Free PMC article.
Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner.
Tsuchihara K, Lapin V, Bakal C, Okada H, Brown L, Hirota-Tsuchihara M, Zaugg K, Ho A, Itie-Youten A, Harris-Brandts M, Rottapel R, Richardson CD, Benchimol S, Mak TW. Tsuchihara K, et al. Among authors: itie youten a. Cancer Res. 2005 Aug 1;65(15):6685-91. doi: 10.1158/0008-5472.CAN-04-4223. Cancer Res. 2005. PMID: 16061649
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW. McIlwain DR, et al. Among authors: itie youten a. Science. 2012 Jan 13;335(6065):229-32. doi: 10.1126/science.1214448. Science. 2012. PMID: 22246778 Free PMC article.