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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.
Genes Dev. 2008 Oct 1;22(19):2677-91. doi: 10.1101/gad.1695308. Epub 2008 Sep 19.
Genes Dev. 2008.
PMID: 18805989
Free PMC article.
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway.
Wilhelm MT, Rufini A, Wetzel MK, Tsuchihara K, Inoue S, Tomasini R, Itie-Youten A, Wakeham A, Arsenian-Henriksson M, Melino G, Kaplan DR, Miller FD, Mak TW.
Wilhelm MT, et al. Among authors: itie youten a.
Genes Dev. 2010 Mar 15;24(6):549-60. doi: 10.1101/gad.1873910. Epub 2010 Mar 1.
Genes Dev. 2010.
PMID: 20194434
Free PMC article.
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Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.
McIlwain DR, Pan Q, Reilly PT, Elia AJ, McCracken S, Wakeham AC, Itie-Youten A, Blencowe BJ, Mak TW.
McIlwain DR, et al. Among authors: itie youten a.
Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12186-91. doi: 10.1073/pnas.1007336107. Epub 2010 Jun 21.
Proc Natl Acad Sci U S A. 2010.
PMID: 20566848
Free PMC article.
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Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner.
Tsuchihara K, Lapin V, Bakal C, Okada H, Brown L, Hirota-Tsuchihara M, Zaugg K, Ho A, Itie-Youten A, Harris-Brandts M, Rottapel R, Richardson CD, Benchimol S, Mak TW.
Tsuchihara K, et al. Among authors: itie youten a.
Cancer Res. 2005 Aug 1;65(15):6685-91. doi: 10.1158/0008-5472.CAN-04-4223.
Cancer Res. 2005.
PMID: 16061649
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iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW.
McIlwain DR, et al. Among authors: itie youten a.
Science. 2012 Jan 13;335(6065):229-32. doi: 10.1126/science.1214448.
Science. 2012.
PMID: 22246778
Free PMC article.
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