Ito K - Search Results

1

Cancer neovasculature-targeted near-infrared photoimmunotherapy (NIR-PIT) for gastric cancer: different mechanisms of phototoxicity compared to cell membrane-targeted NIR-PIT.

Nishimura T, Mitsunaga M, Ito K, Kobayashi H, Saruta M. Nishimura T, et al. Among authors: ito k. Gastric Cancer. 2020 Jan;23(1):82-94. doi: 10.1007/s10120-019-00988-y. Epub 2019 Jul 13. Gastric Cancer. 2020. PMID: 31302791 Free PMC article.

2

Molecular targeted photoimmunotherapy for HER2-positive human gastric cancer in combination with chemotherapy results in improved treatment outcomes through different cytotoxic mechanisms.

Ito K, Mitsunaga M, Arihiro S, Saruta M, Matsuoka M, Kobayashi H, Tajiri H. Ito K, et al. BMC Cancer. 2016 Jan 25;16:37. doi: 10.1186/s12885-016-2072-0. BMC Cancer. 2016. PMID: 26810644 Free PMC article.

3

Combination photoimmunotherapy with monoclonal antibodies recognizing different epitopes of human epidermal growth factor receptor 2: an assessment of phototherapeutic effect based on fluorescence molecular imaging.

Ito K, Mitsunaga M, Nishimura T, Kobayashi H, Tajiri H. Ito K, et al. Oncotarget. 2016 Mar 22;7(12):14143-52. doi: 10.18632/oncotarget.7490. Oncotarget. 2016. PMID: 26909859 Free PMC article.

4

Near-Infrared Photochemoimmunotherapy by Photoactivatable Bifunctional Antibody-Drug Conjugates Targeting Human Epidermal Growth Factor Receptor 2 Positive Cancer.

Ito K, Mitsunaga M, Nishimura T, Saruta M, Iwamoto T, Kobayashi H, Tajiri H. Ito K, et al. Bioconjug Chem. 2017 May 17;28(5):1458-1469. doi: 10.1021/acs.bioconjchem.7b00144. Epub 2017 Apr 26. Bioconjug Chem. 2017. PMID: 28402624 Free PMC article.

5

Antimicrobial strategy for targeted elimination of different microbes, including bacterial, fungal and viral pathogens.

Mitsunaga M, Ito K, Nishimura T, Miyata H, Miyakawa K, Morita T, Ryo A, Kobayashi H, Mizunoe Y, Iwase T. Mitsunaga M, et al. Among authors: ito k. Commun Biol. 2022 Jul 4;5(1):647. doi: 10.1038/s42003-022-03586-4. Commun Biol. 2022. PMID: 35788695 Free PMC article.

6

Photoimmunotechnology as a powerful biological tool for molecular-based elimination of target cells and microbes, including bacteria, fungi and viruses.

Iwase T, Ito K, Nishimura T, Miyakawa K, Ryo A, Kobayashi H, Mitsunaga M. Iwase T, et al. Among authors: ito k. Nat Protoc. 2023 Nov;18(11):3390-3412. doi: 10.1038/s41596-023-00874-z. Epub 2023 Oct 4. Nat Protoc. 2023. PMID: 37794073 Review.

7

Acquired resistance to trastuzumab/pertuzumab or to T-DM1 in vivo can be overcome by HER2 kinase inhibition with TAS0728.

Irie H, Kawabata R, Fujioka Y, Nakagawa F, Itadani H, Nagase H, Ito K, Uchida J, Ohkubo S, Matsuo K. Irie H, et al. Among authors: ito k. Cancer Sci. 2020 Jun;111(6):2123-2131. doi: 10.1111/cas.14407. Epub 2020 Apr 30. Cancer Sci. 2020. PMID: 32248641 Free PMC article.

8

The novel VEGF receptor/MET-targeted kinase inhibitor TAS-115 has marked in vivo antitumor properties and a favorable tolerability profile.

Fujita H, Miyadera K, Kato M, Fujioka Y, Ochiiwa H, Huang J, Ito K, Aoyagi Y, Takenaka T, Suzuki T, Ito S, Hashimoto A, Suefuji T, Egami K, Kazuno H, Suda Y, Nishio K, Yonekura K. Fujita H, et al. Among authors: ito k, ito s. Mol Cancer Ther. 2013 Dec;12(12):2685-96. doi: 10.1158/1535-7163.MCT-13-0459. Epub 2013 Oct 18. Mol Cancer Ther. 2013. PMID: 24140932

9

TAS0728, A Covalent-binding, HER2-selective Kinase Inhibitor Shows Potent Antitumor Activity in Preclinical Models.

Irie H, Ito K, Fujioka Y, Oguchi K, Fujioka A, Hashimoto A, Ohsawa H, Tanaka K, Funabashi K, Araki H, Kawai Y, Shimamura T, Wadhwa R, Ohkubo S, Matsuo K. Irie H, et al. Among authors: ito k. Mol Cancer Ther. 2019 Apr;18(4):733-742. doi: 10.1158/1535-7163.MCT-18-1085. Epub 2019 Feb 20. Mol Cancer Ther. 2019. PMID: 30787176

10

Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors.

Sootome H, Fujita H, Ito K, Ochiiwa H, Fujioka Y, Ito K, Miura A, Sagara T, Ito S, Ohsawa H, Otsuki S, Funabashi K, Yashiro M, Matsuo K, Yonekura K, Hirai H. Sootome H, et al. Among authors: ito k, ito s. Cancer Res. 2020 Nov 15;80(22):4986-4997. doi: 10.1158/0008-5472.CAN-19-2568. Epub 2020 Sep 24. Cancer Res. 2020. PMID: 32973082

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