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Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition.
Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, Gomez MV, Guatimosim C, Wetsel WC, Kushmerick C, Pereira GS, Gainetdinov RR, Izquierdo I, Caron MG, Prado MA. Prado VF, et al. Among authors: izquierdo i. Neuron. 2006 Sep 7;51(5):601-12. doi: 10.1016/j.neuron.2006.08.005. Neuron. 2006. PMID: 16950158 Free article.
Reduced expression of the vesicular acetylcholine transporter causes learning deficits in mice.
de Castro BM, Pereira GS, Magalhães V, Rossato JI, De Jaeger X, Martins-Silva C, Leles B, Lima P, Gomez MV, Gainetdinov RR, Caron MG, Izquierdo I, Cammarota M, Prado VF, Prado MA. de Castro BM, et al. Among authors: izquierdo i. Genes Brain Behav. 2009 Feb;8(1):23-35. doi: 10.1111/j.1601-183X.2008.00439.x. Epub 2008 Sep 6. Genes Brain Behav. 2009. PMID: 18778400 Free article.
The vesicular acetylcholine transporter is required for neuromuscular development and function.
de Castro BM, De Jaeger X, Martins-Silva C, Lima RD, Amaral E, Menezes C, Lima P, Neves CM, Pires RG, Gould TW, Welch I, Kushmerick C, Guatimosim C, Izquierdo I, Cammarota M, Rylett RJ, Gomez MV, Caron MG, Oppenheim RW, Prado MA, Prado VF. de Castro BM, et al. Among authors: izquierdo i. Mol Cell Biol. 2009 Oct;29(19):5238-50. doi: 10.1128/MCB.00245-09. Epub 2009 Jul 27. Mol Cell Biol. 2009. PMID: 19635813 Free PMC article.
Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation.
Martyn AC, De Jaeger X, Magalhães AC, Kesarwani R, Gonçalves DF, Raulic S, Guzman MS, Jackson MF, Izquierdo I, Macdonald JF, Prado MA, Prado VF. Martyn AC, et al. Among authors: izquierdo i. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17651-6. doi: 10.1073/pnas.1215381109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045697 Free PMC article.
Behavioral and genoprotective effects of Vaccinium berries intake in mice.
Barros D, Amaral OB, Izquierdo I, Geracitano L, do Carmo Bassols Raseira M, Henriques AT, Ramirez MR. Barros D, et al. Among authors: izquierdo i. Pharmacol Biochem Behav. 2006 Jun;84(2):229-34. doi: 10.1016/j.pbb.2006.05.001. Epub 2006 Jun 21. Pharmacol Biochem Behav. 2006. PMID: 16797063
635 results