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Many cuts to ruin: a comprehensive update of caspase substrates.
Fischer U, Jänicke RU, Schulze-Osthoff K. Fischer U, et al. Among authors: janicke ru. Cell Death Differ. 2003 Jan;10(1):76-100. doi: 10.1038/sj.cdd.4401160. Cell Death Differ. 2003. PMID: 12655297 Free PMC article. Review.
The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.
Neise D, Sohn D, Stefanski A, Goto H, Inagaki M, Wesselborg S, Budach W, Stühler K, Jänicke RU. Neise D, et al. Among authors: janicke ru. Cell Death Dis. 2013 Oct 17;4(10):e859. doi: 10.1038/cddis.2013.386. Cell Death Dis. 2013. PMID: 24136223 Free PMC article.
Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1).
Sohn D, Budach W, Jänicke RU. Sohn D, et al. Among authors: janicke ru. Cell Death Differ. 2011 Oct;18(10):1664-74. doi: 10.1038/cdd.2011.34. Epub 2011 Apr 8. Cell Death Differ. 2011. PMID: 21475302 Free PMC article.
Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.
Sohn D, Graupner V, Neise D, Essmann F, Schulze-Osthoff K, Jänicke RU. Sohn D, et al. Among authors: janicke ru. Cell Death Differ. 2009 Jun;16(6):869-78. doi: 10.1038/cdd.2009.17. Epub 2009 Feb 20. Cell Death Differ. 2009. PMID: 19229248
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance.
Friedrich K, Wieder T, Von Haefen C, Radetzki S, Jänicke R, Schulze-Osthoff K, Dörken B, Daniel PT. Friedrich K, et al. Oncogene. 2001 May 17;20(22):2749-60. doi: 10.1038/sj.onc.1204342. Oncogene. 2001. PMID: 11420687
Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAF1/CIP1.
Neise D, Sohn D, Budach W, Jänicke RU. Neise D, et al. Among authors: janicke ru. Cell Cycle. 2010 Sep 1;9(17):3575-83. doi: 10.4161/cc.9.17.12799. Epub 2010 Sep 25. Cell Cycle. 2010. PMID: 20818156
The do's and don'ts of p53 isoforms.
Jänicke RU, Graupner V, Budach W, Essmann F. Jänicke RU, et al. Biol Chem. 2009 Oct;390(10):951-63. doi: 10.1515/BC.2009.093. Biol Chem. 2009. PMID: 19453282 Review.
Functional characterization of p53beta and p53gamma, two isoforms of the tumor suppressor p53.
Graupner V, Schulze-Osthoff K, Essmann F, Jänicke RU. Graupner V, et al. Among authors: janicke ru. Cell Cycle. 2009 Apr 15;8(8):1238-48. doi: 10.4161/cc.8.8.8251. Epub 2009 Apr 23. Cell Cycle. 2009. PMID: 19305147
The multiple battles fought by anti-apoptotic p21.
Jänicke RU, Sohn D, Essmann F, Schulze-Osthoff K. Jänicke RU, et al. Cell Cycle. 2007 Feb 15;6(4):407-13. doi: 10.4161/cc.6.4.3855. Epub 2007 Feb 19. Cell Cycle. 2007. PMID: 17312393
Friend or foe? The proteasome in combined cancer therapy.
Sohn D, Totzke G, Schulze-Osthoff K, Jänicke RU. Sohn D, et al. Among authors: janicke ru. Cell Cycle. 2006 Apr;5(8):841-5. doi: 10.4161/cc.5.8.2740. Epub 2006 Apr 17. Cell Cycle. 2006. PMID: 16628002 Review.
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